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Design, Synthesis and Biological Evaluation of 6-(2,6-dichloro-3,5-dimethoxyphenyl)-4-Substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors
Tyrosine kinase fibroblast growth factor receptor (FGFR), which is aberrant in various cancer types, is a promising target for cancer therapy. Here we reported the design, synthesis, and biological evaluation ...
Human Activity Recognition Based on Quantization on Feature’s Classification Capability
Motion related human activity recognition using wearable sensors can potentially enable various useful daily applications. So far, most studies view it as a stand-alone mathematical classification problem without considering the ...
Optimal Surface Amino-Functionalization Following Thermo-Alkaline Treatment of Nanostructured Silica Adsorbents for Enhanced and Selective CO2 Adsorption
Special preparation of SBA-15 materials has been carried out for creating adsorbents exhibiting an enhanced and selective adsorption toward CO2. This creation starts from an adequate conditioning of the silica ...

News & Announcements

Top Read and Downloaded Preprints
Over the past months, we have the chance to announce some very high quality preprints. Here is a selection of the most read and most downloaded articles to date.Most viewed: 688,112 Statistical ...
Crossref and Preprints
Crossref is the organisation that issues persistent identifiers for academic digital content, known as digital object identifiers (DOIs). They do a great job at creating a unique link to content ...
Publishing in Peer-Reviewed Journals after Archiving on Preprints
The majority of journals now support archival of working papers (preprints) on a public server in advance of peer-review and formal publication. Authors can visit the Sherpa database before uploading ...


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Authors upload their manuscript and supplementary files via the online submission system.
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Preprints editors carry out initial checks on content, decisions are made within 24 hours.
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Archived & Online
Preprints that pass the initial checks are posted online, are immediately citable and open for comments.
All Research Fields
All Research Fields
All Research Fields
We accept preprints from all fields, so your article will always be a good fit.
Permanent Archiving
Permanent Archiving
Permanent Archiving
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All preprints receive a digital object identifier (doi) to make them immediately citable.
High visibility
High visibility
High visibility
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Article-Level Metrics
Article-Level Metrics
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