PreprintReviewVersion 1Preserved in Portico This version is not peer-reviewed
Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics
Version 1
: Received: 22 April 2024 / Approved: 22 April 2024 / Online: 23 April 2024 (13:12:55 CEST)
How to cite:
Meja, T.; Wolde, T.; Sahilu, E. Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics. Preprints2024, 2024041476. https://doi.org/10.20944/preprints202404.1476.v1
Meja, T.; Wolde, T.; Sahilu, E. Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics. Preprints 2024, 2024041476. https://doi.org/10.20944/preprints202404.1476.v1
Meja, T.; Wolde, T.; Sahilu, E. Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics. Preprints2024, 2024041476. https://doi.org/10.20944/preprints202404.1476.v1
APA Style
Meja, T., Wolde, T., & Sahilu, E. (2024). Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics. Preprints. https://doi.org/10.20944/preprints202404.1476.v1
Chicago/Turabian Style
Meja, T., Tesfaye Wolde and Elshaday Sahilu. 2024 "Minireview on the Use of Probiotics, Prebiotics, and Synbiotics in Modulating Disturbance of Gastrointestinal Microbiota: An Alternative Therapy to Antibiotics" Preprints. https://doi.org/10.20944/preprints202404.1476.v1
Abstract
Antibiotic prescription is the first line of treating bacterial diseases. But it affects the composition and function of non-targeted intestinal microbiota. Antimicrobial resistance will be the cause for the death of millions of people worldwide. By considering collateral damage of antibiotics, searching an alternative antimicrobial agent will be a solution to minimize the problems. Probiotics, prebiotics and synbiotics are an alternative to antibiotics. Thanks to GIT microbes as they are responsible for metabolism, energy production, protection from pathogens and immunomodulation. So, it is appreciable if the gut microbiota modulated through consumption of probiotics, prebiotics and synbiotics. Probiotic effects are genus and species specific. To get good health benefit of probiotics, safety of probiotics should be assessed before using them. This is mandatory for prebiotics and synbiotic selection. So this review paper gives information about side effects of antibiotics on gut microbiota, description of probiotics, prebiotics and synbiotics as alternative to antibiotics in modulating GIT microbiota, techniques of assessing safety of probiotics and health benefits of probiotics, prebiotics and synbiotics with scientific evidence in clinical trial and some disagreement and challenges of using probiotics, prebiotics and synbiotics.
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
