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Chemical Terroir in Forest Understories: Hypothesis, Ecological Co-Cultivation, and Research Priorities for Saponin-Rich Medicinal Herbs
Quang Vuong Le
,Thi Minh Chau Dao
,Anh Dung Nguyen
,Thi Thao Nguyen
,Thi Bich Lien Nguyen
Posted: 13 May 2026
Protocol Optimization for In Vitro Propagation of Orange-Fleshed Sweet Potato (Ipomoea batatas L.)
Adane Gebeyehu
,Rodomiro Ortiz
,Solomon Tamiru
Posted: 13 May 2026
Microbial Communities in Natural Mineral Waters of Bulgaria: Diversity and Biotechnological Potential
Aleksandar Slavov
,Ilia Tamburadzhiev
,Bogdan Goranov
Posted: 13 May 2026
Spatial Distribution, Seasonal Variation, and Ecological Risk Assessment of Heavy Metals in Tropical Mangrove Wetlands Across Hainan Island, China
Xin Huang
,Yuxing Ma
,Hanxun Qiu
,Kiaenat Nazir
,Yajun Shi
,Jiliang Zhang
Posted: 13 May 2026
Fixed Oil from Caryocar coriaceum: Chemical Composition, Nutritional Relevance, Biological Activities, and Current Translational Challenges
Fixed Oil from Caryocar coriaceum: Chemical Composition, Nutritional Relevance, Biological Activities, and Current Translational Challenges
Joice Barbosa do Nascimento
,Natália Kelly Gomes de Carvalho
,José Galberto Martins da Costa
Caryocar coriaceum Wittm. (Caryocaraceae) is a native Brazilian species predominantly distributed in Cerrado areas and transitional regions with the Caatinga in Northeastern Brazil, whose fruits exhibit significant nutritional, technological, and biofunctional potential. This review systematizes and critically analyzes the available scientific evidence regarding the fixed oil extracted from its fruits, addressing extraction methods, chemical composition, physicochemical parameters, nutritional value, technological applications, and the main bioactivities described in experimental models. Chromatographic and bromatological studies demonstrate that the oil presents a lipid profile characterized by the predominance of monounsaturated and saturated fatty acids, especially oleic acid and palmitic acid, in addition to the presence of carotenoids, phenolic compounds, and other bioactive lipophilic constituents. Available preclinical evidence indicates antioxidants, anti-inflammatory, wound-healing, gastroprotective, respiratory, anticonvulsant, and microbial resistance-modulating properties, suggesting potential applications in the food, pharmaceutical, cosmetic, and biotechnological fields. From the perspective of Food Science, the oil demonstrates characteristics compatible with lipid matrices of functional interest, although aspects related to oxidative stability, compositional standardization, sensory acceptability, and industrial scale-up remain insufficiently explored. Additionally, important limitations persist regarding the scarcity of systematic toxicological studies, the absence of clinical trials in humans, and the limited elucidation of the molecular mechanisms involved in the observed bioactivities. Thus, although C. coriaceum presents promising biotechnological potential, the advancement of its translational application will depend on multidisciplinary approaches capable of integrating chemical standardization, toxicological safety, and applied technological development.
Caryocar coriaceum Wittm. (Caryocaraceae) is a native Brazilian species predominantly distributed in Cerrado areas and transitional regions with the Caatinga in Northeastern Brazil, whose fruits exhibit significant nutritional, technological, and biofunctional potential. This review systematizes and critically analyzes the available scientific evidence regarding the fixed oil extracted from its fruits, addressing extraction methods, chemical composition, physicochemical parameters, nutritional value, technological applications, and the main bioactivities described in experimental models. Chromatographic and bromatological studies demonstrate that the oil presents a lipid profile characterized by the predominance of monounsaturated and saturated fatty acids, especially oleic acid and palmitic acid, in addition to the presence of carotenoids, phenolic compounds, and other bioactive lipophilic constituents. Available preclinical evidence indicates antioxidants, anti-inflammatory, wound-healing, gastroprotective, respiratory, anticonvulsant, and microbial resistance-modulating properties, suggesting potential applications in the food, pharmaceutical, cosmetic, and biotechnological fields. From the perspective of Food Science, the oil demonstrates characteristics compatible with lipid matrices of functional interest, although aspects related to oxidative stability, compositional standardization, sensory acceptability, and industrial scale-up remain insufficiently explored. Additionally, important limitations persist regarding the scarcity of systematic toxicological studies, the absence of clinical trials in humans, and the limited elucidation of the molecular mechanisms involved in the observed bioactivities. Thus, although C. coriaceum presents promising biotechnological potential, the advancement of its translational application will depend on multidisciplinary approaches capable of integrating chemical standardization, toxicological safety, and applied technological development.
Posted: 13 May 2026
On the Observability and Structural Identifiability of Radiobiological Models and the Case for Latent-State Adaptive Control
Vaitheeswaran R
Posted: 13 May 2026
A Single Point Mutation in GraS Drives Co-Evolution of Vancomycin Resistance and Virulence in Staphylococcus aureus
Zhen Hu
,Yifan Rao
,Lu Liu
,Zuwen Guo
,Yuting Wang
,Weilong Shang
,Huagang Peng
Posted: 12 May 2026
Evolving Landscape of Regenerative Therapies: Cell-Based and Cell-Free Approaches for Chronic Low Back Pain
Courtney E. Bartlett
,Pareeshe Bansal
,Siddhant Bhattacharya
,Abhi Dhote
,Bruna B. Nicoletto
,Joana RN Lemos
,Rahul Mittal
Posted: 12 May 2026
Field Evidence for Vertical Transmission of Avian Metapneumovirus Subtype B in Naturally Infected Broiler Breeder Chickens in Egypt
Omar S. Saeed
,Sara A. Shabana
,Basem M. Ahmed
,Ayman H. El-Deeb
,Haitham M. Amer
Posted: 12 May 2026
Hemoglobin Mass as a Determinant of Inter-Individual Susceptibility to Carbon Monoxide Poisoning
Alexandros Sotiridis
,Anastasios Makris
,Nickos D. Geladas
,Maria Koskolou
Posted: 12 May 2026
Single-Cell and Machine Learning Analyses Identify a PFKFB3-Centered Regulatory Network and Potential Salidroside Interaction in Coronary Heart Disease
Haobo Yang
,Yonghui Zhang
,Yunfeng Yu
,Yanan Bai
,Jiale Zhu
,Ouying Chen
,Liping Wang
,Weixiong Jian
Posted: 12 May 2026
Retrovirus-Induced Immunosuppression: A Comprehensive Review
Joachim Denner
Posted: 12 May 2026
Osmosis as a Redox Process: Evidence from the Loop of Henle
Johan Nygren
Posted: 12 May 2026
Cultured Meat Adoption Intention in the Context of Sustainable Protein Transition: Evidence from Young Urban Meat-Eating Adults in Chad
Anna Maria Kaczmarek
Posted: 12 May 2026
Biological Consequences of Microplastic Exposure in Zebrafish (Danio rerio): A Systematic Review Across Developmental, Physiological, and Neurobehavioral Endpoints
Assiddik Sapii Yahsin
,Carlito Baltazar Tabelin
,Theerayut Phengsaart
,Aileen H. Orbecido
,William Ka Fai Tse
,Yukiko Ogino
,Mylah Villacorte-Tabelin
Posted: 12 May 2026
Endogenous Circadian Rhythms in Plant Bioelectric Signals: Cross-Station Replication and Visitor-Driven Suppression in a Public Exhibition
Peter A. Gloor
Posted: 12 May 2026
Metabolomics and Chemometrics for Discrimination and Detection of Buffalo Meat Adulteration in Beef
Chirasak Phoemchalard
,Neungrutai Senarath
,Patcharee Malila
,Tanom Tathong
,Ronnachai Prommachart
Posted: 12 May 2026
Integrative Analysis of Flight Performance Data Using Basic Machine Learning Approaches in Racing Homing Pigeons (Columba livia)
Nursen Senturk
,Ozden Cobanoglu
,Sena Ardicli
Posted: 11 May 2026
Effect of Aptamin C on NK Cell Activity and Cytotoxicity In Vivo and In Vitro: A Comparison Study with the Effect of Vitamin C
Hyovin Ahn
,June Lee
,Jeong-Ho Park
,Jae Sang Barn
,Yejin Kim
,Jae Seung Kang
Posted: 11 May 2026
Large Language Model as a Promising Framework for the Complete Clinical Interpretation of Human Genetic Variants
Jihun Bhak
,Dong-Hyun Shin
,Jongbum Jeon
,Soobok Joe
,Yeonsu Jeon
,Hyoungjin Choi
,Yoonsung Kwon
,Kyungwhan An
,Yun Sung Cho
,Sungwon Jeon
+2 authors
Posted: 11 May 2026
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