Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Insights into Pediatric Sleep Disordered Breathing: Exploring Risk Factors, Surgical Interventions, and Long-Term Neuropsychological Outcomes

Version 1 : Received: 15 February 2024 / Approved: 16 February 2024 / Online: 16 February 2024 (07:41:16 CET)

A peer-reviewed article of this Preprint also exists.

Zaffanello, M.; Pietrobelli, A.; Zoccante, L.; Sacchetto, L.; Nosetti, L.; Piazza, M.; Piacentini, G. Insights into Pediatric Sleep Disordered Breathing: Exploring Risk Factors, Surgical Interventions, and Physical and Scholastic Performance at Follow-Up. Children 2024, 11, 388. Zaffanello, M.; Pietrobelli, A.; Zoccante, L.; Sacchetto, L.; Nosetti, L.; Piazza, M.; Piacentini, G. Insights into Pediatric Sleep Disordered Breathing: Exploring Risk Factors, Surgical Interventions, and Physical and Scholastic Performance at Follow-Up. Children 2024, 11, 388.

Abstract

(1) Background: Sleep disordered breathing represent a growing public health concern, especially among children and adolescents. Full-night polysomnography is considered the gold standard for diagnosing obstructive sleep apnea. Our goals are to identify personal and environmental risk factors for the onset and persistence of sleep respiratory disorders. We also want to investigate the differences in neuropsychological profiles; (2) Methods: This is an observational, retrospective cohort study. We collected information on adenoidectomy or adenotonsillectomy. We reviewed the clinical history and preoperative visits and collected data through a telephone questionnaire. Pediatric Sleep Questionnaire (PSQ) and the Pediatric Quality of Life Inventory (PedsQL) are questionnaires used for screening sleep respiratory disorders in children. The data were statistically analyzed it using SPSS version 22.0 for Windows (SPSS Inc., Chicago, IL); (3) Results: The study involved 138 patients, but only 100 parents participated. A higher percentage of patients with sleep disordered breathing were observed to have mothers who smoked during pregnancy. A smaller proportion of patients with sleep disordered breathing had a habit of using a pacifier. A rise in physical results is associated with a reduction in the PSQ at follow-up (p=0.051). An increase of overall academic achievement is associated with an average decrease in the PSQ at follow-up (p<0.0001). A more significant proportion of patients undergoing adenotonsillectomy were observed to have a history of prematurity and cesarean birth (4) Conclusions: These results provide essential information on the effectiveness and effects of adenotonsillectomy intervention compared to adenoidectomy intervention and the factors associated with SDB in children undergoing these interventions.

Keywords

adenoidectomy; adenotonsillectomy; breastfeeding; children; obstructive sleep apnea; quality of life; Pediatric Sleep Questionnaire; sleep-disordered breathing

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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