Version 1
: Received: 10 February 2024 / Approved: 12 February 2024 / Online: 14 February 2024 (03:44:40 CET)
How to cite:
Pucker, B. Functional Annotation – How to Tackle the Bottleneck in Plant Genomics. Preprints2024, 2024020645. https://doi.org/10.20944/preprints202402.0645.v1
Pucker, B. Functional Annotation – How to Tackle the Bottleneck in Plant Genomics. Preprints 2024, 2024020645. https://doi.org/10.20944/preprints202402.0645.v1
Pucker, B. Functional Annotation – How to Tackle the Bottleneck in Plant Genomics. Preprints2024, 2024020645. https://doi.org/10.20944/preprints202402.0645.v1
APA Style
Pucker, B. (2024). Functional Annotation – How to Tackle the Bottleneck in Plant Genomics. Preprints. https://doi.org/10.20944/preprints202402.0645.v1
Chicago/Turabian Style
Pucker, B. 2024 "Functional Annotation – How to Tackle the Bottleneck in Plant Genomics" Preprints. https://doi.org/10.20944/preprints202402.0645.v1
Abstract
This review provides an overview of advancements in plant genomics, emphasizing key stages in genomics projects and addressing associated challenges. Long read sequencing enables the cost-effective sequencing of plant DNA and assembly of highly continuous genome sequences - often even separating haplophases. Incorporating external hints, such as cDNA sequences from RNA-seq or full length cDNA sequencing, enhances the identification of gene models. While these steps enable high-throughput exploration of numerous plant genomes, a significant bottleneck lies in elucidating gene functions. The classical approach based on wet lab methods is impractical when dealing with thousands of genes in a new genome sequence. To overcome this challenge, computational tools harnessing existing information for cross species knowledge transfer are essential for expediting the functional annotation process. In support of researchers entering the field of plant genomics, a collection of recommended tools has been curated and is accessible at https://github.com/bpucker/ToolOverview.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
