Version 1
: Received: 22 January 2024 / Approved: 7 February 2024 / Online: 7 February 2024 (12:59:53 CET)
How to cite:
Al Baloushi, M.; Saleh, H.; Ahmed, B.; Konje, J.C. Congenital Viral Infections: Consequences on the Mother and Fetus and Management. Preprints2024, 2024020447. https://doi.org/10.20944/preprints202402.0447.v1
Al Baloushi, M.; Saleh, H.; Ahmed, B.; Konje, J.C. Congenital Viral Infections: Consequences on the Mother and Fetus and Management. Preprints 2024, 2024020447. https://doi.org/10.20944/preprints202402.0447.v1
Al Baloushi, M.; Saleh, H.; Ahmed, B.; Konje, J.C. Congenital Viral Infections: Consequences on the Mother and Fetus and Management. Preprints2024, 2024020447. https://doi.org/10.20944/preprints202402.0447.v1
APA Style
Al Baloushi, M., Saleh, H., Ahmed, B., & Konje, J.C. (2024). Congenital Viral Infections: Consequences on the Mother and Fetus and Management. Preprints. https://doi.org/10.20944/preprints202402.0447.v1
Chicago/Turabian Style
Al Baloushi, M., Badreldeen Ahmed and Justin C Konje. 2024 "Congenital Viral Infections: Consequences on the Mother and Fetus and Management" Preprints. https://doi.org/10.20944/preprints202402.0447.v1
Abstract
Viruses are the most common congenital infections and an important cause of fetal malformations, morbidity, and mortality. The effects of these infections, which are transmitted in-utero (transplacentally), during childbirth or in the puerperium depend on the timing of the infections. These vary from miscarriages (usually with infections in very early pregnancy), congenital malformations (where the infections occur during organogenesis) and morbidity (with infections occurring late in pregnancy, during childbirth or after delivery). The most common of these viruses are cytomegalovirus, hepatitis, parvovirus B-19, rubella, varicella and zika. There are currently very few efficacious antiviral agents licensed for use in pregnancy and therefore for most of these infections, prevention by means of immunisation (where there is a vaccine), administration of immunoglobulins to those exposed to the virus to offer passive immunity or appropriate measures to avoid being infected would be options to minimise the infections and their consequences. In this review, we discuss the current understanding of some of the congenital infections and their consequences on both the mother and fetus and their management focusing mainly on prevention.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
