Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Shock Index VS Modified Shock Index as a Predictor of Mortality among the COVID-19 Patients

Version 1 : Received: 19 January 2024 / Approved: 19 January 2024 / Online: 22 January 2024 (08:12:12 CET)

How to cite: S, A.; Trichur, R.V.; Cattamanchi, S.; Vijayan, P. Shock Index VS Modified Shock Index as a Predictor of Mortality among the COVID-19 Patients. Preprints 2024, 2024011519. https://doi.org/10.20944/preprints202401.1519.v1 S, A.; Trichur, R.V.; Cattamanchi, S.; Vijayan, P. Shock Index VS Modified Shock Index as a Predictor of Mortality among the COVID-19 Patients. Preprints 2024, 2024011519. https://doi.org/10.20944/preprints202401.1519.v1

Abstract

Introduction: The viral respiratory disorder known as severe acute respiratory syndrome (SARS) is caused by the SARS-associated coronavirus. End of May 2021, there have been over 170 million reported cases and more than 3.53 million deaths worldwide. In the field of cardiovascular performance, the shock index (SI) is a simple and widely used formula that measures the physiological response prior to systemic hypotension. It is obtained by dividing the heart rate by the systolic blood pressure. Another parameter, the modified shock index (MSI), is defined as the ratio of heart rate to mean arterial pressure (MAP). Methods: In this retrospective study, we examined the data of COVID-19 patients who were admitted to the ICU between June 1st, 2020, and January 31st, 2021. The patient details were collected from the Medical Records Department (MRD) in a tertiary care center. A case-recorded proforma was used to record the patient information, which was then analyzed using SPSS software. Results: The mean age of the patients was 67 years, consisting of 64 males (68.9%) and 29 females (31.1%). The standard deviation was calculated as 13.557. Among the patients, the minimum age recorded was 28, while the maximum age was 97. Patients with known CAD (Coronary Artery Disease) had a higher mortality rate among comorbidities. The p-value for Shock Index and Mortality Status was 0.205 (with an alpha value greater than 0.05), indicating no significant association. However, the modified shock index (MSI) showed a significant association with mortality status. The Pearson chi-square value for MSI and Mortality Status was 4.19, with a p-value of 0.041 (with an alpha value less than 0.05). These results suggest that there is a higher risk of mortality for patients with a Modified Shock Index of less than 0.7 or greater than 1.3. The MSI Odds ratio was found to be 4.500, indicating that such patients have a 4.5 times higher risk of mortality compared to others. Conclusion: In conclusion, our study found that there is no significant association between the Shock Index (SI) and mortality, as the p-value was greater than 0.05. However, the Modified Shock Index (MSI) showed a significant association with mortality status, with a p-value less than 0.05. This suggests that patients with a Modified Shock Index less than 0.7 or greater than 1.3 are at a higher risk of mortality. It is important to consider these findings when assessing the prognosis and potential interventions for COVID-19 patients.

Keywords

Shock Index; Modified Shock Index; COVID-19; Mortality

Subject

Medicine and Pharmacology, Emergency Medicine

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