Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Primary Bone Lymphoma of the Scapula with an Unexpected Complication

Version 1 : Received: 17 January 2024 / Approved: 18 January 2024 / Online: 18 January 2024 (10:29:02 CET)

A peer-reviewed article of this Preprint also exists.

Lovaković, J.; Mandac Smoljanović, I.; Matković, A.; Smoljanović, T. Primary Bone Lymphoma of the Scapula. Hematol. Rep. 2024, 16, 106-113. Lovaković, J.; Mandac Smoljanović, I.; Matković, A.; Smoljanović, T. Primary Bone Lymphoma of the Scapula. Hematol. Rep. 2024, 16, 106-113.

Abstract

Primary bone lymphoma of the scapula is a rare tumor that usually causes local pain. Presented patient suffered for two years from paresthesia, tingling, numbness, and edema of the little and ring finger. The 45-year-old man underwent several radiological and neurological assessments of the palm, elbow and neck prior to radiographs revealing the tumor of the left shoulder. Once diffuse large B cell lymphoma was confirmed, immunochemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and methylprednisolone (R-CHOP) started. The treatment was accompanied by antiviral treatment with lamivudine due to positive hepatitis B virus serology and with bisphosphonate treatment for the prevention of bone resorption. Once immunochemotherapy was finished, the treatment was supplemented by radiotherapy of the shoulder. After more than three years of accomplishing remission, the patient had an ischemic stroke manifesting with right-sided hemiparesis. Following the physical therapy, the patient is currently in the process of evaluation for thrombophilia, as well as further cardiac assessment due to the positive transcranial Doppler bubble test setting high suspicion for the presence of patent foramen ovale.

Keywords

Primary bone lymphoma; scapula; diffuse large B cell lymphoma; immunochemotherapy; radiotherapy

Subject

Medicine and Pharmacology, Hematology

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