Version 1
: Received: 19 December 2023 / Approved: 19 December 2023 / Online: 19 December 2023 (15:57:37 CET)
How to cite:
Eltokhy, A.K.; El-Abbasi, A.M.; Eltoukhi, M.K.; Seddiki, S.M.L.; Ghannoum, M.A. The Escalating Specter of Antifungal Resistance in Superficial Mycoses. Preprints2023, 2023121446. https://doi.org/10.20944/preprints202312.1446.v1
Eltokhy, A.K.; El-Abbasi, A.M.; Eltoukhi, M.K.; Seddiki, S.M.L.; Ghannoum, M.A. The Escalating Specter of Antifungal Resistance in Superficial Mycoses. Preprints 2023, 2023121446. https://doi.org/10.20944/preprints202312.1446.v1
Eltokhy, A.K.; El-Abbasi, A.M.; Eltoukhi, M.K.; Seddiki, S.M.L.; Ghannoum, M.A. The Escalating Specter of Antifungal Resistance in Superficial Mycoses. Preprints2023, 2023121446. https://doi.org/10.20944/preprints202312.1446.v1
APA Style
Eltokhy, A.K., El-Abbasi, A.M., Eltoukhi, M.K., Seddiki, S.M.L., & Ghannoum, M.A. (2023). The Escalating Specter of Antifungal Resistance in Superficial Mycoses. Preprints. https://doi.org/10.20944/preprints202312.1446.v1
Chicago/Turabian Style
Eltokhy, A.K., Sidi Mohammed lahbib Seddiki and Mahmoud Afif Ghannoum. 2023 "The Escalating Specter of Antifungal Resistance in Superficial Mycoses" Preprints. https://doi.org/10.20944/preprints202312.1446.v1
Abstract
Superficial mycoses, encompassing a range of fungal infections affecting the outer layers of the skin, hair, and nails, have become increasingly prevalent in recent years. While these infections are generally non-life-threatening, the emergence of antifungal resistance poses a growing threat to effective treatment strategies. In this article we explore the escalating specter of antifungal resistance in superficial mycoses, focusing on the underlying mechanisms driving resistance, the clinical implications, and potential avenues for mitigation. The rise of antifungal resistance in superficial mycoses is multifactorial. Consequently, the efficacy of conventional treatments is diminishing, leading to persistent or recurrent infections. Understanding the molecular mechanisms underlying antifungal resistance is crucial for developing targeted therapeutic approaches. Research efforts aimed at unraveling these mechanisms are essential for identifying new drug targets and designing innovative treatment strategies to combat resistant strains. In response to the escalating threat of antifungal resistance, a multifaceted approach is required. This includes enhanced surveillance of antifungal susceptibility patterns, the development of novel antifungal agents, and the implementation of stringent guidelines for antifungal use. Additionally, educational initiatives targeting healthcare professionals and the public are essential to promote responsible antifungal use, reduce the risk of resistance emergence, and improve treatment outcomes.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
