Version 1
: Received: 12 December 2023 / Approved: 13 December 2023 / Online: 14 December 2023 (09:27:50 CET)
How to cite:
Vlase, C.M.; Iancu, A.; Stefan, C.; Draghiev, I.; Dumitru, C.; Arbune, M. Multidrug-Resistant ESKAPE Pathogens in a Romanian Secondary-Care Hospital during the COVID-19 Pandemic. Preprints2023, 2023121017. https://doi.org/10.20944/preprints202312.1017.v1
Vlase, C.M.; Iancu, A.; Stefan, C.; Draghiev, I.; Dumitru, C.; Arbune, M. Multidrug-Resistant ESKAPE Pathogens in a Romanian Secondary-Care Hospital during the COVID-19 Pandemic. Preprints 2023, 2023121017. https://doi.org/10.20944/preprints202312.1017.v1
Vlase, C.M.; Iancu, A.; Stefan, C.; Draghiev, I.; Dumitru, C.; Arbune, M. Multidrug-Resistant ESKAPE Pathogens in a Romanian Secondary-Care Hospital during the COVID-19 Pandemic. Preprints2023, 2023121017. https://doi.org/10.20944/preprints202312.1017.v1
APA Style
Vlase, C.M., Iancu, A., Stefan, C., Draghiev, I., Dumitru, C., & Arbune, M. (2023). Multidrug-Resistant ESKAPE Pathogens in a Romanian Secondary-Care Hospital during the COVID-19 Pandemic. Preprints. https://doi.org/10.20944/preprints202312.1017.v1
Chicago/Turabian Style
Vlase, C.M., Caterina-Nela Dumitru and Manuela Arbune. 2023 "Multidrug-Resistant ESKAPE Pathogens in a Romanian Secondary-Care Hospital during the COVID-19 Pandemic" Preprints. https://doi.org/10.20944/preprints202312.1017.v1
Abstract
The ESKAPE pathogens are public health concerns worldwide, defining the present major antibiotic resistance issues: E. faecium vancomycin-R, S. aureus methicillin-R, Ps. Aeruginosa and A. baumannii carbapenem-R, resistance to 3rd generation cephalosporins of Kl. pneumoniae and Enterobacter spp. Covid-19 pandemic disturbed the health care usual procedures, contributing to the spread of antibiotic-resistant bacteria. The present study retrospectively assessed the prevalence and antimicrobial resistance (AMR) profile of ESKAPE microorganisms during 2020-2022 in a multidisciplinary emergency hospital from Romania, based on microbiological reports. The AMR issues mainly interest the urology department. ESKAPE group accounts for 33.5% of the total bacterial isolated. The specific AMR of ESKAPE pathogens cumulates 30.9%, while antimicrobial multidrug resistance characterizes 21% from all ESKAPE strains. Kl. Pneumoniae, followed by S. aureus, and Ps. aeruginosa are the main hospital problems concerning the ESKAPE surveillance. The directions of the near future antibiotic stewardship program focus to revise the clinical protocols for diagnostic and treatment in each department, to intensify the bacteriological samples collection, to improve the microbiological diagnostic techniques for AMR identification, to continue the epidemiological current actions of surveillance, control, and education.
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
