Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Are We Ready to Recommend Capsaicin for Disorders Other than Neuropathic Pain?

Version 1 : Received: 26 September 2023 / Approved: 26 September 2023 / Online: 27 September 2023 (15:42:58 CEST)

A peer-reviewed article of this Preprint also exists.

Silva, J.L.; Santos, E.A.; Alvarez-Leite, J.I. Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain? Nutrients 2023, 15, 4469. Silva, J.L.; Santos, E.A.; Alvarez-Leite, J.I. Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain? Nutrients 2023, 15, 4469.

Abstract

Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili peppers. In recent years, a significant increase in investigations into its properties has allowed the production of new formulations and the development of tools with biotechnological, diagnostic, and potential therapeutic applications. In this way, the possible clinical application of such compound is expanding every year. This opinion article aims to provide a synthesis of recent findings regarding the mechanisms by which capsaicin participates in the control of non-communicable diseases such as obesity, diabetes, and dyslipidemia. This opinion review also discusses the recent findings and clinical studies of the use of capsaicin in body weight control.

Keywords

capsaicin, pepper, diabetes, obesity, inflammation, gut microbiota

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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