Alharbi, R.M.; Abdel-Raouf, N.; Omar, R.; Hassan, S.; Elsayed, K.N.; Ibraheem, I.B.M. Bioengineering and Assessment of Antibacterial Potential for Silver Nanoparticles Derived from Synechococcus sp.. Preprints2023, 2023091584. https://doi.org/10.20944/preprints202309.1584.v1
APA Style
Alharbi, R.M., Abdel-Raouf, N., Omar, R., Hassan, S., Elsayed, K.N., & Ibraheem, I.B.M. (2023). Bioengineering and Assessment of Antibacterial Potential for Silver Nanoparticles Derived from <em>Synechococcus</em> sp.. Preprints. https://doi.org/10.20944/preprints202309.1584.v1
Chicago/Turabian Style
Alharbi, R.M., Khaled N.M. Elsayed and Ibraheem Borie M. Ibraheem. 2023 "Bioengineering and Assessment of Antibacterial Potential for Silver Nanoparticles Derived from <em>Synechococcus</em> sp." Preprints. https://doi.org/10.20944/preprints202309.1584.v1
Abstract
Abstract: Given the increasing resistance of some bacterial strains to many common antibiotics used in the local market, the current study aimed to produce nanoscale particles capable of combating pathogenic bacteria that have developed resistance to current antibiotics. In this research, an ex-perimental study was conducted to produce nanoscale particles using the single-celled blue-green algae Synechococcus sp., which was isolated from a local environment in the Arab Republic of Egypt, specifically from a soil sample in Beni-Suef City. The aim of the study was to generate silver NPs employing different biological approaches, encompassing the direct strain powder technique, ethanol extract pellet technique, and ethanol extract technique. These synthesized nanoparticles displayed different shapes, including cubic, spherical, pellet-like, and rod-shaped particles. They were characterized by bio-functional groups containing Ag+ ions, which were detected using FT-IR, Zeta sizer, and Zeta potential measurements. High-resolution SEM imaging unveiled the mor-phological features of Silver NPs with biologically formed protective layers, spanning sizes from 20 to 430 nm for individual particles. The study evaluated the antibacterial efficiency against both G+ve and G-ve bacteria. The ethanolic extract technique exhibited the largest inhibition zone (24 mm) against G+ve bacteria, particularly Staphy. aureus. Furthermore, it was observed that the larger particles produced using the powder and pellet techniques were less effective antibacterial agents. In conclusion, this investigation emphasizes the potential of cyanobacteria-based synthesis of silver nanoparticles as a promising approach for producing innovative antimicrobial agents.
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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