Version 1
: Received: 31 July 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (10:08:44 CEST)
How to cite:
Arokiaraj, M.C.; Wilson, J.; Lu, J.; Huang, R. Streptococcus pneumoniae and Influenza (H1N1) virus Genome Study Against Human Genome Sequences – Blastn and DAVID Analysis. Preprints2023, 2023080171. https://doi.org/10.20944/preprints202308.0171.v1
Arokiaraj, M.C.; Wilson, J.; Lu, J.; Huang, R. Streptococcus pneumoniae and Influenza (H1N1) virus Genome Study Against Human Genome Sequences – Blastn and DAVID Analysis. Preprints 2023, 2023080171. https://doi.org/10.20944/preprints202308.0171.v1
Arokiaraj, M.C.; Wilson, J.; Lu, J.; Huang, R. Streptococcus pneumoniae and Influenza (H1N1) virus Genome Study Against Human Genome Sequences – Blastn and DAVID Analysis. Preprints2023, 2023080171. https://doi.org/10.20944/preprints202308.0171.v1
APA Style
Arokiaraj, M.C., Wilson, J., Lu, J., & Huang, R. (2023). <em>Streptococcus pneumoniae</em> and Influenza (H1N1) virus Genome Study Against Human Genome Sequences – Blastn and DAVID Analysis. Preprints. https://doi.org/10.20944/preprints202308.0171.v1
Chicago/Turabian Style
Arokiaraj, M.C., Jingqiao Lu and RuoPan Huang. 2023 "<em>Streptococcus pneumoniae</em> and Influenza (H1N1) virus Genome Study Against Human Genome Sequences – Blastn and DAVID Analysis" Preprints. https://doi.org/10.20944/preprints202308.0171.v1
Abstract
Aim:Streptococcus pneumoniae and influenza H1N1 virus are common organisms associated with human infections. These infections could play a significant role in immune regulation. The study was performed to analyse the genome sequences of these organisms with human genome and study its functional significance. Methods: The study was performed to analyse the overlapping of genome sequences in Streptococcus pneumoniae and Influenza (H1N1) virus against human genome sequences by BLASTn sequence analysis. The alignments are studied against the corresponding genes for their functional significance with DAVID and NDEx software.Results: Several hits or overlapping nucleotide segments were identified. Between streptococcus and homo sapiens 287 overlaps were identified, and among influenza and homo sapiens 124 hits were identified. A wide range of functional significance of these genes were identified, and the results are presented in this study. The results show insights into functional pathways and biological activities associated with the respective vaccinations or infections by these microorganisms. Conclusion: The common organisms like Streptococcus pneumoniae and Influenza H1N1 virus actively interact with the immune system and result in a wide range of immune regulations.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
