Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Long-term Outcomes of Birdshot Chorioretinopathy Treated With Corticosteroids: A Retrospective Cohort Study

Dino Ferracci
* ,
Thibaud Mathis
ORCID logo ,
Antoin Gavoille
,
Mathieu Gerfaud-Valentin
ORCID logo ,
Arthur Bert
,
Meriem Hafidi
,
Philippe Denis
,
Olivier Loria
,
Laurent Kodjikian
ORCID logo ,
Pascal Sève
* ORCID logo
Version 1 : Received: 11 June 2023 / Approved: 12 June 2023 / Online: 12 June 2023 (07:17:49 CEST)

A peer-reviewed article of this Preprint also exists.

Ferracci, D.; Mathis, T.; Gavoille, A.; Gerfaud-Valentin, M.; Bert, A.; Hafidi, M.; Denis, P.; Loria, O.; Kodjikian, L.; Sève, P. Long-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports. J. Clin. Med. 2023, 12, 5288. Ferracci, D.; Mathis, T.; Gavoille, A.; Gerfaud-Valentin, M.; Bert, A.; Hafidi, M.; Denis, P.; Loria, O.; Kodjikian, L.; Sève, P. Long-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports. J. Clin. Med. 2023, 12, 5288.

Abstract

Purpose: To report the progression of patients diagnosed with birdshot chorioretinopathy (BSCR) initially treated with corticosteroids. Methods: We included 39 BSCR patients followed for ≥1 year. Patients were classified into 2 groups according to their initial treatment: methylprednisolone followed by prednisone (n=28) and prednisone alone (n=11). We analyzed the progression under treatment after 1, 3, 6 months, 1 year, and at the end of follow-up. Results: At the end of follow-up, 31/39 (79.5%) patients had reached inflammation control. Thirteen out of 28 (46.4%) and 6/11 (54.5%) patients were treated exclusively with corticosteroids, and 18/19 (94.7%) of them had reached inflammation control at the end of follow-up; their mean (range) corticosteroid dose was 3.5 (0-10) mg/day. Conclusion: We found that the prolonged corticosteroid therapy treatment strategy resulted in inflammation control in half of BSCR patients. This control was maintained with low doses of cortisone, usually <5 mg/day.

Keywords

birdshot chorioretinopathy (BSCR); corticosteroids; inflammatory macular edema; prognosis; relapse; uveitis.

Subject

Medicine and Pharmacology, Ophthalmology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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