Version 1
: Received: 21 February 2023 / Approved: 23 February 2023 / Online: 23 February 2023 (15:34:27 CET)
How to cite:
Amorim, R.; Silva, V.T.; Martins, H.O.; Brasil, S.; Godoy, D.; Mendes, M.T.; Gattas, G.; Bor-Seng-Shu, E.; Paiva, W. Role of Perfusion Tomography in Traumatic Acute Subdural Hematoma: A Pilot Study. Preprints2023, 2023020411. https://doi.org/10.20944/preprints202302.0411.v1
Amorim, R.; Silva, V.T.; Martins, H.O.; Brasil, S.; Godoy, D.; Mendes, M.T.; Gattas, G.; Bor-Seng-Shu, E.; Paiva, W. Role of Perfusion Tomography in Traumatic Acute Subdural Hematoma: A Pilot Study. Preprints 2023, 2023020411. https://doi.org/10.20944/preprints202302.0411.v1
Amorim, R.; Silva, V.T.; Martins, H.O.; Brasil, S.; Godoy, D.; Mendes, M.T.; Gattas, G.; Bor-Seng-Shu, E.; Paiva, W. Role of Perfusion Tomography in Traumatic Acute Subdural Hematoma: A Pilot Study. Preprints2023, 2023020411. https://doi.org/10.20944/preprints202302.0411.v1
APA Style
Amorim, R., Silva, V.T., Martins, H.O., Brasil, S., Godoy, D., Mendes, M.T., Gattas, G., Bor-Seng-Shu, E., & Paiva, W. (2023). Role of Perfusion Tomography in Traumatic Acute Subdural Hematoma: A Pilot Study. Preprints. https://doi.org/10.20944/preprints202302.0411.v1
Chicago/Turabian Style
Amorim, R., Edson Bor-Seng-Shu and Wellingson Paiva. 2023 "Role of Perfusion Tomography in Traumatic Acute Subdural Hematoma: A Pilot Study" Preprints. https://doi.org/10.20944/preprints202302.0411.v1
Abstract
Introduction: CT perfusion (CTP) is an alternative tool to assess cerebral hemodynamics in brain trauma. As traumatic acute subdural hematomas (ASH) are severe lesions commonly associated with poor outcome, we aimed to evaluate the brain hemodynamics in this population. Methods: Five patients admitted at the emergency department sustaining traumatic acute subdural hematoma were evaluated. Preoperative CTP was performed immediately after nonenhanced head CT scan. Postoperative CTP was performed in four patients. The outcome was assessed 6 months after surgery using the extended Glasgow Outcome Scale. Results: 4 male and 1 female were evaluated. Mean age was 46y (SD: 8.1). Mean preoperative midline brain shift was 10.1 mm (SD: 1.8). The main mechanism of trauma was falling (four patients). There was a general improvement in cerebral blood flow (CBF) after surgery from 23.9 (SD: 6.1) to 30.7 ml/100g/min, (SD: 5.1) and in mean transit time (MTT) from 7.3 (SD: 1.3) to 5.8s (SD:1.0), although it is not statistically significant (p=0.06 and p=0.06, respectively). There was still a reduction in the cerebral blood volume (CBV) media when compared to the value after surgery, from 2.63 (SD: 1.10) to 2.34 ml/100g (SD: 0.67), which is not statistically significant (p=0.31). Spearman correlation test of postoperative and preoperative CBF ratio with outcome was 0.94 (p=0.054). Only one patient died (three days after surgery). This patient was victim of car crash and had the highest preoperative MTT (9.97 seconds) and CBV (4.51 ml/100 g). Conclusion: Post-operative improvement of hemodynamic CTP parameters may be correlated with outcomes after ASH. Further studies with larger samples are required to confirm this hypothesis.
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
