Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Factors Associated With Mortality With Tuberculosis Diagnosis in Indigenous Population in Peru 2015-2019

Version 1 : Received: 10 August 2022 / Approved: 11 August 2022 / Online: 11 August 2022 (12:00:20 CEST)

A peer-reviewed article of this Preprint also exists.

León-Giraldo, H.; Rivera-Lozada, O.; Castro-Alzate, E.S.; Aylas-Salcedo, R.; Pacheco-López, R.; Bonilla-Asalde, C.A. Factors Associated with Mortality with Tuberculosis Diagnosis in Indigenous Populations in Peru 2015–2019. Int. J. Environ. Res. Public Health 2022, 19, 15019. León-Giraldo, H.; Rivera-Lozada, O.; Castro-Alzate, E.S.; Aylas-Salcedo, R.; Pacheco-López, R.; Bonilla-Asalde, C.A. Factors Associated with Mortality with Tuberculosis Diagnosis in Indigenous Populations in Peru 2015–2019. Int. J. Environ. Res. Public Health 2022, 19, 15019.

Abstract

Aim. To identify factors associated with mortality with tuberculosis diagnosis in the indigenous population in Peru 2015-2019. Methods. Case-control study nested in a retrospective cohort, using the registry of persons belonging to indigenous peoples of the National Tuberculosis Prevention and Control Strategy of the Ministry of Health of Peru. A descriptive analysis was applied, and then bivariate and multiple logistic regression was used to evaluate associations between the variables and the outcome (live-deceased), the results were presented as OR with their respective 95% confidence intervals. Results. The mortality rate of the total indigenous population of Peru was 1.75 deaths per 100,000 indigenous people diagnosed with TB. The community of Kukama kukamiria - Yagua reported 505 (28.48%) individuals. The final logistic model showed that indigenous men (OR=1.93; 95% CI: 1.001-3.7), with a history of HIV prior to TB (OR=16.7; 95% CI: 4.7-58.7) and indigenous people in old age (OR=2.95; 95% CI: 1.5-5.7), are factors associated with a greater chance of dying from TB. Conclusions. It is important to reorient health services among indigenous populations, especially those related to improving the timely diagnosis and early treatment of TB-HIV co-infection, to ensure comprehensive care for this population, considering that they are vulnerable groups.

Keywords

Tuberculosis; Mortality; Indigenous; Logistic Regression

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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