Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants

Version 1 : Received: 5 July 2022 / Approved: 6 July 2022 / Online: 6 July 2022 (15:27:32 CEST)

How to cite: Caspari, T. From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants. Preprints 2022, 2022070100. https://doi.org/10.20944/preprints202207.0100.v1 Caspari, T. From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants. Preprints 2022, 2022070100. https://doi.org/10.20944/preprints202207.0100.v1

Abstract

The successive waves of the Covid-19 pandemic are driven by SARS-CoV-2 variants that reached critical detection levels in different parts of the world. But how evolved the Wuhan virus since its detection in December 2019 into the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529) variants of concern? This is a story of mice and men, of up to 1,000,000 infected cells in one person, where each cell produces between 105 and 106 viral RNAs, of immune-compromised patients, the digestive tract and viral recombination.

Keywords

omicron; alpha; delta; deltacron; recombination; RNA editing; intra-host variants; tropisms; ox-idative damage; Wuhan

Subject

Biology and Life Sciences, Virology

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