Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Collaborative Semantic Annotation Tooling (CoAT) to Improve Efficiency and Plug-and-Play Semantic Interoperability in Secondary Use of Medical Data: Concept, Implementation, and First Cross-Institutional Experiences

Version 1 : Received: 12 January 2024 / Approved: 13 January 2024 / Online: 15 January 2024 (06:20:41 CET)

A peer-reviewed article of this Preprint also exists.

Wiktorin, T.; Grigutsch, D.; Erdfelder, F.; Heidel, A.J.; Bloos, F.; Ammon, D.; Löbe, M.; Zenker, S. Collaborative Semantic Annotation Tooling (CoAT) to Improve Efficiency and Plug-and-Play Semantic Interoperability in the Secondary Use of Medical Data: Concept, Implementation, and First Cross-Institutional Experiences. Appl. Sci. 2024, 14, 820. Wiktorin, T.; Grigutsch, D.; Erdfelder, F.; Heidel, A.J.; Bloos, F.; Ammon, D.; Löbe, M.; Zenker, S. Collaborative Semantic Annotation Tooling (CoAT) to Improve Efficiency and Plug-and-Play Semantic Interoperability in the Secondary Use of Medical Data: Concept, Implementation, and First Cross-Institutional Experiences. Appl. Sci. 2024, 14, 820.

Abstract

Cross-institutional secondary use of medical data benefits from structured semantic annotation, which, ideally, enables matching and merging semantically related data items from different sources and sites. While numerous medical terminologies and ontologies, as well as some tooling, exist to support such annotation, cross-institutional data usage based on independently annotated datasets is challenging for multiple reasons: the annotation process is resource intensive and requires a combination of medical and technical expertise since it often requires judgment calls to resolve ambiguities resulting from non-uniqueness of potential mappings to various levels of ontological hierarchies and relational and representational systems. Divergent resolution of such ambiguities can inhibit joint cross-institutional data usage based on semantic annotation since data items with related content from different sites will not be identifiable based on their respective annotations if different choices were made without further steps such as ontological inference, which is still an active area of research. We hypothesize that a collaborative approach to semantic annotation of medical data can contribute to more resource efficient and high-quality annotation by utilizing prior annotational choices of others to inform the annotation process, thus both speeding up the annotation itself and fostering a consensus approach to resolving annotational ambiguities by enabling annotators to discover and follow pre-existing annotational choices. Therefore, we have implemented a prototypical Collaborative Annotation Tool (CoAT), evaluated its usability, and present first inter-institutional experiences with this novel approach to promoting practically relevant interoperability driven by use of standardized ontologies.

Keywords

semantic annotation; medical data; annotation tool; terminology; SNOMED CT; LOINC; ATC; interoperability; reusability

Subject

Computer Science and Mathematics, Software

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