Mpofana, N.; Yalo, M.; Gqaleni, N.; Dlova, N.C.; Hussein, A.A. Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. Int. J. Mol. Sci.2024, 25, 237.
Mpofana, N.; Yalo, M.; Gqaleni, N.; Dlova, N.C.; Hussein, A.A. Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. Int. J. Mol. Sci. 2024, 25, 237.
Mpofana, N.; Yalo, M.; Gqaleni, N.; Dlova, N.C.; Hussein, A.A. Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. Int. J. Mol. Sci.2024, 25, 237.
Mpofana, N.; Yalo, M.; Gqaleni, N.; Dlova, N.C.; Hussein, A.A. Analysis of Three Species of Cassipourea Traditionally Used for Hypermelanosis in Selected Provinces in South Africa. Int. J. Mol. Sci. 2024, 25, 237.
Abstract
There is a growing demand and use of herbal cosmetics for skin purposes due to their perceived safety when applied to the skin. Three Cassipourea species commonly known as “ummemezi” are used interchangeable by women in rural areas of Eastern Cape and KwaZulu-Natal provinces to treat hypermelanosis as well as sun protection. We conducted a phytochemical comparison of three Cassipourea species; C. flanaganii, C. gummiflua and C. malosana by LC-MS/MS analysis in negative mode. The results obtained from the LC-MS/MS yielded a total number of twenty-four compounds of different chemical classes, including fatty acids, steroids, di- and tri-terpenoids, flavonoids, phenolic acids were detected, and eighteen among them were tentatively identified. Despite the recent popularity of modern cosmetic products, it is clear that plants continue to play an important role in the local cosmetics industry in South Africa's Eastern Cape and KwaZulu-Natal community provinces. The findings of this study suggest that an alternative treatment for hyper-melanosis disorders should be developed further. The residual wild plant stocks are insufficient to meet commercial needs, thus, encouraging their sustainable use is a means of harnessing the conservation of these plants. Indigenous communities should be supported in the commercialization which could be linked to the rural economic development.
Chemistry and Materials Science, Medicinal Chemistry
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