Kim, J.-Y.; Kim, S.-G.; Garagiola, U. Relevant Properties and Potential Applications of Sericin in Bone Regeneration. Curr. Issues Mol. Biol.2023, 45, 6728-6742.
Kim, J.-Y.; Kim, S.-G.; Garagiola, U. Relevant Properties and Potential Applications of Sericin in Bone Regeneration. Curr. Issues Mol. Biol. 2023, 45, 6728-6742.
Kim, J.-Y.; Kim, S.-G.; Garagiola, U. Relevant Properties and Potential Applications of Sericin in Bone Regeneration. Curr. Issues Mol. Biol.2023, 45, 6728-6742.
Kim, J.-Y.; Kim, S.-G.; Garagiola, U. Relevant Properties and Potential Applications of Sericin in Bone Regeneration. Curr. Issues Mol. Biol. 2023, 45, 6728-6742.
Abstract
The potential of sericin, a protein derived from silkworms, is explored in bone graft applications. Sericin's biocompatibility, hydrophilic nature, and cost-effectiveness make it a promising candidate for enhancing traditional graft materials. Its antioxidant, anti-inflammatory, and UV-resistant properties contribute to a healthier bone-healing environment, and its incorporation into 3D-printed grafts could lead to personalized medical solutions. However, despite these promising attributes, there are still gaps in our understanding. The precise mechanism through which sericin influences bone cell growth and healing is not fully understood, and more comprehensive clinical trials are needed to confirm its long-term biocompatibility in humans. Furthermore, the best methods for incorporating sericin into existing graft materials are still under investigation, and potential allergic reactions or immune responses to sericin need further study.
Keywords
Sericin; Bone graft applications; Biocompatibility; Immune responses; Tissue engineering; Bone healing
Subject
Chemistry and Materials Science, Biomaterials
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
