Preprint Article Version 1 NOT YET PEER-REVIEWED

Large Scale Screening of Southern African Plant Extracts for the Green Synthesis of Gold Nanoparticles using Microtitre-Plate Method

  1. DST/Mintek Nanotechnology Innovation Center, Department of Biotechnology, University of the Western Cape, Private Bag X17, Bellville 7530, South Africa
  2. South African National Biodiversity Institute, Compton Herbarium, Private bag X7, Claremont 7735, South Africa
  3. Department of Biodiversity and Conservation Biology, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa
  4. Department of Chemistry, University of the Western Cape, Private Bag X17, Bellville 7530, South Africa
Version 1 : Received: 10 August 2016 / Approved: 11 August 2016 / Online: 11 August 2016 (09:53:19 CEST)

A peer-reviewed article of this Preprint also exists.

Elbagory, A.M.; Cupido, C.N.; Meyer, M.; Hussein, A.A. Large Scale Screening of Southern African Plant Extracts for the Green Synthesis of Gold Nanoparticles Using Microtitre-Plate Method. Molecules 2016, 21, 1498. Elbagory, A.M.; Cupido, C.N.; Meyer, M.; Hussein, A.A. Large Scale Screening of Southern African Plant Extracts for the Green Synthesis of Gold Nanoparticles Using Microtitre-Plate Method. Molecules 2016, 21, 1498.

Journal reference: Molecules 2016, 21, 1498
DOI: 10.3390/molecules21111498

Abstract

The preparation of gold nanoparticles (AuNPs) involves a variety of chemical and physical methods. These methods use toxic and environmentally harmful chemicals. Consequently, the synthesis of AuNPs using green chemistry has been under investigation to develop eco-friendly nanoparticles. One method to achieve this is the use of plant-derived phytochemicals capable of reducing gold ions to produce AuNPs. The aim of this study was to implement a facile microtitre-plate method to screen a large number of aqueous plant extracts to determine the optimum concentration (OC) to bio-synthesize the AuNPs. Several AuNPs of different sizes and shapes were successfully synthesized and characterized from seventeen South African plants. The characterization was done using Ultra Violet-Visible Spectroscopy, Dynamic Light Scattering, High Resolution Transmission Electron Microscopy and Energy-Dispersive X-ray Spectroscopy. We also studied the effects of temperature on the synthesis of the nanoparticles and measured its effect on the particle size of the synthesized AuNPs and the data showed that changes in temperatures affect the size and dispersity of the generated AuNPs. Further, some of the synthesized AuNPs were stable upon incubation with different biological solutions in vitro.

Subject Areas

green nanotechnology; gold nanoparticles; biosynthesis; high resolution transmission electron microscopy; Cape flora

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