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Review
Medicine and Pharmacology
Cardiac and Cardiovascular Systems

Roberto Nerla

,

Martina Mandas

,

Gianluca Pillitteri

,

Elisa Mikus

,

Niki Bernardoni

,

Angelo Squeri

,

Davide Pacini

,

Carlo Savini

,

Fausto Castriota

Abstract: Mitral valve regurgitation is the second most common valvular heart disease in Europe, and an estimated 10% of individuals older than 75 years have severe mitral regurgitation. Mitral valve repair is the preferred strategy to treat mitral regurgitation and is associated with better outcomes than mitral valve replacement. Despite the proven efficacy of surgical repair, available data in functional aetiologies reported a not negligible rate of echocardiographically detected severe mitral regurgitation within ten years of the index procedure, in some cases resulting in redo interventions. Data on the optimal management of patients with failed mitral repair remain limited. The aim of this review is to present the available approaches for treating failed mitral valve repair and to describe criteria for selecting the most appropriate strategy on the basis of the underlying mechanism of repair failure, with respect to possible surgical re-repair and novel transcatheter edge-to-edge repair techniques in presence of favourable mitral valve anatomies.

Article
Computer Science and Mathematics
Data Structures, Algorithms and Complexity

Kexin Guo

,

Jingwen Wang

,

Jiayu Lin

,

Ningjing Chen

,

Hengyuan Chen

,

Zilang Zhou

,

Manzhou Li

Abstract: To address the problems of strong noise, high asynchrony, pronounced subjectivity in risk labels, and insufficient model stability under extreme market conditions in multi-source risk signals within trading environments, a low-noise investment risk prediction method based on multimodal sensing signals and self-supervised representation learning is proposed. Market quotations, order books, terminal interactions, network transmission, device status, and news sentiment are uniformly modeled as risk perception signals. A temporal masking-based risk structure modeling module, a risk-oriented contrastive learning representation constraint mechanism, and a risk representation and downstream prediction task alignment strategy are designed to learn stable, transferable, and interpretable risk features. Experimental results show that the proposed method achieves the best performance in investment risk prediction, with mean squared error (MSE), mean absolute error (MAE), and root mean square error (RMSE) reaching 0.0164, 0.0851, and 0.1281, respectively, outperforming baseline models including generalized autoregressive conditional heteroskedast (GARCH), multi-layer perceptron (MLP), long short term memory (LSTM), temporal convolutional networks (TCN), and Transformer. The IC, RankIC, and AUC reach 0.496, 0.462, and 0.817, respectively, indicating stronger risk ranking capability and improved discrimination between high-risk and low-risk states. At the classification recognition level, the proposed method also demonstrates superior accuracy, precision, recall, and F1-score, indicating that potential high-risk assets can be identified more accurately. Ablation experiments verify the effectiveness of multimodal fusion, temporal masking, self-supervised contrastive constraints, and task alignment modules. Robustness experiments further show that lower prediction errors and higher AUC can still be maintained in high-volatility and extreme-shock markets, demonstrating strong noise resistance, stability, and practical application potential in complex sensing scenarios.

Review
Engineering
Architecture, Building and Construction

Augustine Akumasi

,

Joshua Ayarkwa

,

Alex Acheampong

,

Godwin K. K. Acquah

Abstract: The pressing need to minimize cement-related CO₂ emissions attracted the search for agricultural waste ashes as supplementary cementitious materials (SCMs). Agro-waste ashes, rich in silica and alumina, are promising cementitious materials. However, prior researchers reported inconsistent chemical compositions and physical properties due to differences in calcination methods. This systematical review proofed the impact of calcination temperature on the chemical composition, physical properties and pozzolanic performance of agricultural waste ashes. Systematic Literature Review (SLR) following PRISMA protocols, with published articles retrieved from Scopus, Web of Science, Wiley Online Library, and Google Scholar (2014–2025) was used for the study. Using keywords, 524 published articles were first identified; after screening and eminence evaluations, 50 articles met the inclusion criteria. Data was obtained mainly on calcination methods, chemical compositions, physial properties and compliance with standards such as GS 1118 (2016) EN 197-1 (2011) and SANS 50197-1. Comparative analysis disclosed constant deficiencies in CaO (0.91–25.80%) and extreme SiO₂ (40–63%) and Al₂O₃ (10–42%) contents, particularly with open-air burning. The findings emphasized 600–700°C for 90–120 minutes as the best manufacturing window for standard-conformity of ashes derived from agro-waste materials. This review highlighted the importance of controlled calcination, identified research gaps, and provided evidence-based principles for manufacturing SCMs in construction.

Review
Public Health and Healthcare
Public, Environmental and Occupational Health

Izabela Kaczmarek

,

Katarzyna Mokra

,

Jaromir Michałowicz

Abstract: In this review, the occurrence in the environment and human surrounding, as well as toxic action of perfluorooctanoic acid (PFOA) and its selected short-chain analogs – perfluorohexanoic acid (PFHxA) and perfluorobutanoic acid (PFBA) has been described. These substances belong to a group of polyfluoroalkyl substances (PFASs) widely represented in various compartments of the environment, including air, water and soil. They are also present in dust, drinking water and food, which are main sources of the exposure of humans to these compounds. Due to physico-chemical properties PFASs are strongly resistant to degradation in the biosphere and therefore, effectively accumulate in biota, including humans. PFOA has been produced from decades, but due to its toxicity it has been successively replacing by PFASs of shorter chain, including PFHxA and PFBA, which presence in the environment, as well as risk of human exposure and toxicity has been poorly investigated. It has been proven that PFOA reveals hepatotoxic and endocrine-disrupting activities, as well as exhibits prooxidative, immunotoxic, epigenetic and carcinogenic potential. Hitherto conducted researches have shown that PFHxA and PFBA are less toxic than PFOA, nevertheless additional extensive studies should be conducted in order to determine environmental and toxicological status of these compounds.

Article
Biology and Life Sciences
Plant Sciences

Olusegun D. Badewa

,

Elizabeth Parkes

,

Andrew Gana

,

Eli Tsado

,

Kehinde Tolorunse

,

Peter Iluebbey

,

Patrick Akpotuzor

,

Toye Ayankanmi

Abstract: Improving provitamin‑A cassava requires a clear understanding of how key agronomic and nutritional traits respond to seasonal variation and how these traits interact within a multivariate structure. The objectives were to evaluate agronomic and nutritional traits across seasons, apply multivariate analyses to uncover trait domains, and investigate inter‑trait relationships to guide breeding strategies. Forty‑two provitamin‑A cassava accessions were evaluated using a split‑plot randomized complete block design, with genotype as the main‑plot factor and harvest time as the subplot factor, replicated across seasons. Eight traits were measured, with emphasis on DM, FYLD, and TC. Multivariate analyses provided deeper insight into trait structure. Principal component analysis and factor analysis identified distinct trait structures: PCA revealed four trait domains, while factor analysis uncovered three latent trait groupings–Root Productivity (ML2), Vegetative and Compositional Diversity (ML3), and Harvest Efficiency (ML1). Traits such as RTWT and HI exhibited near‑zero uniqueness, reinforcing their roles as anchor indicators of productivity and efficiency, while TC displayed exceptionally high uniqueness, confirming its independence from yield domains and its regulation by distinct metabolic pathways. Biplots highlighted genotype dispersion and trait loadings, hierarchical clustering grouped accessions by combined agronomic and nutritional performance, and a chord diagram confirmed a tightly linked yield complex alongside a separate nutritional domain. Variance component estimates revealed contrasting levels of genetic and environmental influence. DM showed moderate genotypic variance and no significant seasonal effect, underscoring its stability and reliability for processing quality. FYLD exhibited low genotypic variance, high residual variance, and a highly significant season effect, confirming strong environmental sensitivity. TC displayed high genotypic variance and a significant seasonal effect, suggesting that carotenoid accumulation is both genetically controlled and environmentally modulated. The integration of mixed‑model variance partitioning with multivariate and network‑based analyses revealed clear differences in trait stability, genetic control, and inter‑trait relationships. These findings identify DM as a robust trait for selection, FYLD as highly environment‑dependent, and TC as a promising target for biofortification with manageable environmental sensitivity. The results provide a comprehensive model for index‑based selection strategies, guiding breeders toward “stacked” ideotypes that combine high yield potential, stable dry matter content, enhanced carotenoid accumulation, and efficient resource allocation to meet industrial, nutritional, and food security needs across cassava‑growing regions.

Article
Physical Sciences
Mathematical Physics

Cécile Barbachoux

Abstract: The mathematization of science is undergoing a structural transformation driven by the rise of computation and data-intensive methods. While classical mathematization relied on explicitly defined laws and formal structures, contemporary scientific practice increasingly encounters mathematical objects that arise as outcomes of dynamical and algorithmic processes. This paper introduces the notion of computationally emergent structures to describe entities generated and stabilized through the interaction of parameterized models, optimization dynamics, and data. We develop a minimal formal framework in which such structures are characterized as asymptotic outcomes of learning dynamics and show that, in over parameterized regimes, they are selected by implicit variational principles not specified a priori. This framework provides a unified account of implicit regularization, kernel regimes, and stability phenomena in modern learning systems. These results show that contemporary learning systems operate according to implicit variational principles in which geometry, dynamics, and data jointly determine effective mathematical structure. They thereby identify a shift from representation to dynamical emergence, extending the scope of mathematization toward a theory of structure formation grounded in computation.

Article
Social Sciences
Education

Fatma Kaya Orhon

,

Kamil Çekerol

,

Serap Uğur

Abstract: Generative Artificial Intelligence (GenAI) is driving a fundamental paradigm shift in architectural design, transitioning from deterministic drafting to algorithmic curation. While the Architecture, Engineering, and Construction (AEC) sector rapidly adopts these tools, academic curricula face a critical "Techno-Instructional Void." This gap risks inducing a "Zero Order Thinking State" (ZOTS)—a cognitive passivity rooted in Cognitive Load Theory, where students uncritically accept unbuildable machine hallu-cinations. Developed through comprehensive preliminary consultations with academ-ic colleagues and longitudinal studio observations, this study introduces the "Twin Houses" methodology and the "Technical Sealing" protocol. By enforcing "Cognitive Friction," the framework compels students to validate probabilistic GenAI outputs against deterministic physical laws (e.g., Blondel's Formula 2R + T = 63 cm) and safety norms. Crucially, Building Information Modeling (BIM) acts as an automated Proof-Assistant, utilizing visual programming APIs (Revit Dynamo, Allplan Python-Parts) and IFC 4.3 data schemas for rigorous Rule-Based Checking (RBC). To confirm cross-border transferability and optimize the time-costs of curriculum integration via an asynchronous AI-TPACK module, the framework is currently undergoing verifica-tion interviews with a bilateral expert panel (n=8) from Germany and Türkiye. Ulti-mately, this framework provides a structured pedagogical approach, equipping in-structors to guide students in transforming machine hallucinations into legally builda-ble, tectonic realities. Sample videos showcasing student works are available in the Supplementary Materials.

Review
Chemistry and Materials Science
Medicinal Chemistry

Katarzyna Stępnik

Abstract: Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder driven by complex interactions between protein aggregation, oxidative stress, neuroinflammation, and cellular dysfunction. Among plant-derived compounds, curcumin has emerged as one of the most extensively studied polyphenols due to its broad spectrum of biological activities. This review provides a critical synthesis of mechanistic, preclinical, and clinical evidence on curcumin in AD. Experimental studies consistently demonstrate that curcumin modulates key pathogenic processes, including neuroinflammatory signaling, oxidative stress, and amyloid-β aggregation, with more limited evidence for effects on tau pathology. While in vitro studies offer detailed mechanistic insights, in vivo models provide more integrated evidence, including improvements in cognitive performance and reductions in pathological markers. Despite this strong preclinical foundation, clinical evidence remains limited and inconsistent. Randomized controlled trials have not demonstrated clear therapeutic efficacy, with outcomes strongly influenced by formulation, bioavailability, and study design. Poor solubility, rapid metabolism, and limited brain exposure remain key translational barriers. In response, increasing attention has been directed toward formulation strategies and structurally related compounds. Emerging curcuminoids, such as bisdemethoxycurcumin (BDMC), are discussed as potential next-generation candidates. Preliminary evidence suggests that BDMC may modulate oxidative stress, autophagy, astrocyte senescence, and amyloid-related processes, although data remain largely preclinical. Overall, curcumin represents a mechanistically rich and preclinically promising multi-target compound, but with unresolved translational limitations. Future research should prioritize pharmacokinetic optimization, formulation-dependent validation, and exploration of novel curcuminoid strategies to bridge the gap between experimental findings and clinical application in AD.

Review
Chemistry and Materials Science
Materials Science and Technology

Xiaoying Cui

,

Yixin Cao

,

Yiming Dong

,

Rui Song

,

Zhaoping Song

Abstract: Bismuth tungstate (Bi2WO6) is a typical bismuth-based visible-light-responsive semiconductor photocatalyst that has attracted significant attention in the fields of environment remediation and energy conversion. In this paper, to address the issues of high photogenerated carrier recombination rate and limited visible-light response range of Bi2WO6, various modification strategies are highlighted, including morphology control, element doping, heterojunction construction, carbon material compositing, and coupling with functional materials such as MOFs, COFs, or conductive polymers. Furthermore, the structure-activity relationships are discussed. On this basis, the latest application progress of Bi2WO6-based photocatalysts in fields such as pollutant degradation, antibacterial activity, and energy conversion and storage is summarized. Finally, prospects are put forward regarding the existing shortcomings and future development directions in the application of Bi2WO6-based photocatalysts, aiming to provide a systematic theoretical reference for the design and application of high-performance Bi2WO6-based photocatalysts.

Article
Engineering
Marine Engineering

Zhonghua Tan

,

Hanbao Chen

,

Songgui Chen

,

Ning Guan

,

Yingni Luan

,

Wenjun Shen

Abstract: A systematic experimental investigation was conducted on the motion response (RAO) and mooring performance of a novel disk-shaped buoy (geometric scale 1:10) subjected to combined wind, wave, and current actions. A hybrid experimental strategy was employed, integrating a large-scale wave flume (for long-period waves and currents) with a harbor basin (for short-period waves and wind), aiming to mitigate the scale effects inherent in Froude-scaled models, particularly with regard to drag force measurements. The test matrix included free decay in calm water, RAOs under regular waves, motion and mooring line tension under irregular waves, and measurements of wind and current drag coefficients. Key results indicate a natural roll period of approximately 3.0 s with a notably high dimensionless damping ratio (ζ ≈ 0.14–0.15), which is conducive to rapid motion attenuation. A pronounced resonance peak in the roll RAO (26.6°/m) was observed near the 3 s period. Under an extreme sea state (Hₛ = 13.8 m, Tₚ = 16.1 s), the maximum roll angle and dynamic mooring line tension reached 21.30° and 61.56 kN, respectively, the latter being about 3.0 times the static pretension. The mean wind drag coefficient and current drag coefficient were determined as 0.76 and 0.44. This research provides a validated dataset and critical insights for the design, mooring system optimization, and operational safety assessment of such disk-shaped buoys. The effectiveness of the hybrid testing approach is confirmed, and the favorable damping characteristic of this buoy form is highlighted.

Article
Computer Science and Mathematics
Artificial Intelligence and Machine Learning

Gabriel Axel Montes

Abstract: Agentic AI systems plan over time, call tools, write and retrieve memory, and coordinate across modules and services. Some of the most consequential failures in such systems are structural before they are behavioral: hidden coordination, trace-mediated lock-in, seam bottlenecks, and the silent erosion of meaningful override. This position paper argues that agentic AI systems should be evaluated and governed for \textbf{structural governability}, not only output alignment. By structural governability, we mean whether consequential coordination remains observable, attributable, interruptible, and steerable at the seams between components before irreversible commitments occur. Output-only evaluation does not capture this property. We propose an evidence ladder for structural risk in place of any single master metric: architecture-time priors over system structure, runtime coupling signals on telemetry graphs, and deeper state-regime diagnostics for high-stakes cases. We then sketch a research agenda for benchmarks that stress structure rather than terminal task success, reporting standards that disclose control geometry, and seam-level interventions including approval gates, permission freezes, trace decay, rollback, and subsystem isolation. The wider stake is cognitive integrity. Once agentic systems mediate what users retrieve, remember, delegate, and act upon, alignment depends on preserving the conditions under which users and operators can still understand, contest, redirect, and refuse those processes.

Brief Report
Medicine and Pharmacology
Epidemiology and Infectious Diseases

Valentina Gutiérrez

,

Francisco Alcalde

,

Paula Impellizzeri

,

Felipe Lizana

,

Gonzalo Valenzuela

,

Cecilia Vizcaya

,

Ximena Claverie

,

Cristián Sotomayor

,

Daniel Springmüller

,

Nicole Le Corre

Abstract: Isavuconazole is increasingly being used for the treatment of invasive fungal disease (IFD), although real-world pediatric data remain limited. We retrospectively reviewed patients aged ≤18 years who received isavuconazole for fungal infection at two tertiary centers in Chile between 2021 and 2025. Twenty patients were included, with a median age of 13.7 years (IQR, 9.4–15.5); 14 (70%) had an underlying malignancy, and 6 (30%) were allogeneic hematopoietic cell transplant recipients. Isavuconazole was used for treatment in 16 patients and for prophylaxis in 4, predominantly as second-line therapy due to prior antifungal intolerance, inadequate response, drug–drug interactions, or QT prolongation. Fifteen patients had IFD, with Mucorales (n=3) being the most frequently identified pathogens in proven cases and pulmonary involvement predominating in probable IFD. A succesful response at 90 days was achieved in 60% (6/10) of evaluable cases. No breakthrough fungal infections occurred during treatment or prophylaxis. Hepatic enzyme elevations were observed in four patients. Isavuconazole was associated with favorable outcomes and an acceptable safety profile, supporting its use as an alternative antifungal in pediatric patients.

Article
Business, Economics and Management
Business and Management

Wiwik Utami

,

Erna Setiany

,

Rieke Pernamasari

,

Anwar Allah Pitchay

Abstract: This study examines the relationships between innovation, green management implementation, and their effects on business sustainability and value creation in Indonesian healthcare companies. Innovation is measured using Value Added Intellectual Capital (VAIC) efficiency, while green management implementation is proxied by Environmental, Social, and Governance (ESG) scores. Business sustainability is operationalized through carbon disclosure practices, and value creation is measured via Market Value Added (MVA). Using panel data from 30 listed firms (2019–2023) and applying fixed and random effects regression models showed that green management implementation significantly and positively influences carbon disclosure, supporting the role of ESG practices in enhancing sustainability transparency. However, innovation capacity demonstrates no significant direct effects on either carbon disclosure or market value creation, challenging conventional assumptions about intellectual capital's impact on sustainability and value performance. Component-level analysis improves explanatory power, showing that structural capital efficiency has a marginally negative effect on carbon disclosure, while social ESG scores emerge as the strongest driver of transparency. However, neither carbon disclosure nor ESG performance translates into immediate value creation, with MVA explained more by firm-specific characteristics and profitability (ROA). These findings extend intellectual capital and transparency theories by showing how social performance channels shape disclosure practices.

Article
Engineering
Mining and Mineral Processing

Jianhua Chen

,

Lujing Liang

,

Xufu Zhang

,

Anruo Luo

Abstract: Chalcopyrite and molybdenite exhibit similar surface wettability and high floatability, which has long hindered their efficient and selective separation in mineral processing. In this work, the novel chalcopyrite depressant 2-mercapto-5-benzoimidazole sulfonate dihydrate (2MBI5SA) was investigated for its effect on the flotation behavior of chalcopyrite and molybdenite. Compared with the conventional depressant sodium sulfide (Na2S), 2MBI5SA exhibited stronger selective depression toward chalcopyrite; under conditions yielding Mo recovery of 81.46% and a Mo grade of 4.46%, the Cu recovery decreased to 13.03%. To clarify the origin of this selectivity, interfacial properties were systematically characterized using adsorption measurements, contact angle measurements, zeta potential measurements, FT-IR, XPS, and SEM-EDS, and the adsorption mechanism was further elucidated using SCC-DFTB calculations. The results demonstrate that 2MBI5SA chemisorbs onto the chalcopyrite surface via bidentate coordination, forming a stable adsorption layer that effectively suppresses chalcopyrite flotation. Moreover, structure-function relationship analysis confirmed that introducing hydrophilic and ionizable functional groups into the collector framework can convert a collector into a selective depressant, thereby providing new insight into the design of environmentally benign flotation depressants.

Article
Biology and Life Sciences
Biochemistry and Molecular Biology

Olga N. Alekseeva

,

Pavel O. Vorobyev

,

Yasmin Shakiba

,

Stepan A. Ionov

,

Svetlana S. Antseva

,

Anastasia Semenova

,

Marat P. Valikhov

,

Vladimir A. Kalsin

,

Veronika V. Vadekhina

,

Dmitry V. Kochetkov

+2 authors

Abstract: Oncolytic virotherapy offers a promising avenue for solid tumor treatment, yet single-agent approaches are frequently limited by insufficient tumor lysis and inadequate immune activation. Here we report that combined therapy with two recombinant variants of the oncolytic vaccinia virus, armed with either herpes simplex virus thymidine kinase (VV-HSVtk) or the interleukin 15 receptor subunit alpha (VV-mIL15Rα), induces enhanced cytotoxicity and immune stimulation in a murine mammary adenocarcinoma model (4T1). In vitro, VV-HSVtk exhibited dose-dependent cytotoxicity markedly potentiated by ganciclovir (GCV) through HSVtk-mediated phosphorylation into a cytotoxic nucleoside analogue, and co-culture of VV-infected tumor cells with donor-derived NK cells further amplified oncolytic efficiency. In vivo, combined treatment with VV-HSVtk, VV-mIL15Rα, and GCV resulted in significant tumor regression and extended survival relative to monotherapy controls in 4T1 syngeneic mice. Histological examination revealed robust lymphocytic infiltration at tumor sites and absence of hepatic or splenic toxicity. Mechanistically, VV-mIL15Rα-driven IL-15 trans-presentation amplified immune cell activation, while VV-HSVtk/GCV provided targeted tumor debulking and immunogenic cell death, collectively reshaping the immunosuppressive tumor microenvironment. These findings establish a multimodal oncolytic platform combining direct viral cytotoxicity, suicide gene therapy, and cytokine-mediated immune co-stimulation as a translatable strategy for treating solid tumors.

Article
Computer Science and Mathematics
Artificial Intelligence and Machine Learning

Istiaque Bhuiyan

,

Tanvir Bhuiyan

Abstract: Purpose: This study examines whether finance-adapted (FA) phishing detection models improve detection of finance-themed (FT) attacks, whether improvements differ across email and webpage modalities, and whether finance adaptation creates a specialisation–generalisation trade-off. Design/Methodology/Approach: A domain-aware framework is developed using email (164,972 instances) and webpage (11,430 instances) datasets. FT and non-finance-themed (NFT) instances are identified using weighted lexicon-based labelling. Generic models are compared with FA models across Logistic Regression, Linear SVC, and Random Forest using F1-score, MCC, balanced accuracy, ROC-AUC, and PR-AUC. Statistical validation employs bootstrap confidence intervals and McNemar's test, while SHAP and permutation importance interpret webpage model behaviour. Findings: FA models outperform generic models in FT email classification, confirming that finance-specific semantic cues improve detection. However, gains are weaker and less consistent in webpage classification, where models rely mainly on structural indicators (page rank, Google index, hyperlinks). Results reveal a specialisation–generalisation trade-off: FA models improve in-domain detection but do not consistently outperform generic models on NFT instances, with F1-score declines of -0.0057 to -0.0151 on non-finance subsets. Practical Implications: Financial institutions and fintech platforms should deploy domain-adapted detection for email-based threats, where finance-specific linguistic cues yield measurable gains, while maintaining generic or ensemble models for broader webpage phishing coverage. Originality/Value: This study introduces a finance-themed, multi-modal, explainable AI framework for phishing detection, demonstrating that domain adaptation depends critically on data modality and feature representation. It provides a novel systematic comparison of generic versus FA phishing detection across both modalities with statistical validation and explainability analysis.

Article
Engineering
Control and Systems Engineering

Vesela Karlova-Sergieva

Abstract: This study proposes a geometric procedure for robust controller tuning under parametric uncertainty, based on root-contour analysis of the closed-loop control system. For a fixed candidate controller tuning, the set of possible pole locations induced by the admissible variations of the control plant parameters is constructed. Robust admissibility is formulated as a geometric set-inclusion problem, requiring this set to remain inside a prescribed dynamic performance region in the complex s-plane. A distinction is introduced between nominal admissibility, robust stability, and robust admissibility, showing that stability over the entire uncertainty set is not sufficient to guarantee the desired dynamic performance. To quantify the root contours, several indices are defined, including the dispersion along the real and imaginary axes, the maximum pole displacement with respect to the nominal pole locations, and the geometric margin to the boundary of the performance region. The procedure is applied to the selection and verification of PI controller tunings for an uncertain single-input single-output (SISO) control system and is further validated through examples with different structures of parametric uncertainty, including a system with a single uncertain parameter and a PID-controlled system with several uncertain control plant parameters. The results show that root-contour analysis can distinguish tunings that are only robustly stable from tunings that preserve the prescribed dynamic performance over the entire uncertainty set. Thus, the method can be used as a practical tool for the diagnosis, comparison, and selection of controller tunings under parametric uncertainty.

Article
Business, Economics and Management
Economics

Daniel Nigohosyan

,

Albena Vutsova

Abstract: This paper provides the first systematic, cross-country empirical comparison of the Recovery and Resilience Facility (RRF) and Cohesion Policy funds (CPF) in the domain of renewable energy deployment. Covering 14 EU Member States, the analysis combines quantitative cross-country evidence on financing volumes, technology mixes, implementation speed, and reported capacity achievements. The findings show that the RRF represents a major amplification of EU renewable energy financing, with planned allocations exceeding Cohesion Policy expenditure by a factor of five to ten. At the same time, claims of superior performance-based delivery require qualification: green transition financial progress lags the general RRF disbursement rate, milestone fulfilment for renewable energy falls short of planned indicative rates in most countries, and reported operational capacity figures raise plausibility concerns. The analysis reveals no meaningful correlation between milestone and target fulfilment and progress with renewable energy Country-Specific Recommendations, suggesting that administrative compliance with milestones does not immediately translate into structural reform outcomes. These findings carry direct implications for the design of the post-2027 EU financial framework, particularly regarding the stabilisation of performance indicators, the introduction of attribution protocols for reform-linked achievements, and the preservation of complementarity between performance-based and non-performance-based approaches.

Review
Computer Science and Mathematics
Security Systems

Silvie Levy

,

Ehud Gudess

,

Danny Hendler

Abstract: Maritime operations rely on the Automatic Identification System (AIS), an open broadcast protocol whose unauthenticated, self-reported Messages are easily abused. This survey takes an AIS-first, security-focused view, grounded in a comprehensive review of prior AIS-security research. We (i) explain how AIS works and use that to expose fundamental weaknesses; (ii) synthesize from the literature the main threats and their technical and operational impacts; (iii) categorize, from the surveyed works and operational practice, mitigations by the layers they target and, for each mitigation, indicate whether it primarily prevents, detects, responds, or supports recovery; and (iv) provide practical recommendations. Bringing together cybersecurity, maritime operations, and data-science perspectives, we consolidate recommendations for securing AIS-based systems and assess their current use in practice, thus highlighting the gaps that standards and implementations still need to address.

Review
Business, Economics and Management
Finance

Renad Alghamdi

,

Alaa Samoun

,

Abdul Malik Syed

Abstract: This study examines the evolution of research on mergers and acquisitions (M&A) in the banking sector through a bibliometric analysis aimed at identifying the main con-tributors, dominant research themes, and emerging gaps in the literature. The study situates banking M&A research within broader discussions of efficiency, market structure, integration performance, and financial stability, while highlighting the need to better understand how scholarly influence and thematic development shape the field over time. Using bibliometric techniques, the analysis evaluates publication trends, journal con-centration, authorship patterns, international collaboration networks, citation struc-tures, keyword co-occurrence, and thematic mapping. The study synthesizes relation-ships among influential publications, institutions, and countries to assess how ideas circulate and which research themes remain central or underexplored within the liter-ature. The findings reveal a concentrated body of scholarship dominated by a limited number of journals, recurrent author networks, and strong transatlantic collaboration patterns, with relatively limited representation from the Global South. Research themes related to efficiency, firm performance, and market structure occupy the core of the literature, whereas technology integration, sustainability considerations, consumer outcomes, and conduct risk remain comparatively peripheral. Citation patterns are highly une-ven, reflecting a small group of highly influential studies alongside a broader set of context-specific contributions. The analysis also identifies a persistent gap between pre-merger strategic narratives and post-merger integration realities, particularly in relation to operational outcomes and systemic risk considerations. The study concludes that future research would benefit from integrating traditional finance approaches with transaction-level integration measures, governance and op-erational performance indicators, and more robust identification strategies around regulatory and policy shocks. The findings further suggest that banking practitioners should place greater emphasis on integration feasibility, risk-control capabilities, digi-tal transformation readiness, and sustainability considerations when evaluating and implementing merger strategies.

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