Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Single-Facility Analysis of COVID-19 Status of Healthcare Employee During the Eighth and Ninth Pandemic Waves in Japan After Introducing Regular Rapid Antigen Testing

Version 1 : Received: 10 May 2024 / Approved: 13 May 2024 / Online: 13 May 2024 (07:47:10 CEST)

How to cite: Nagasawa, M.; Kato, T.; Sakaguchi, H.; Tanaka, I.; Watanabe, A.; Hiroshima, Y.; Sakurai, M. Single-Facility Analysis of COVID-19 Status of Healthcare Employee During the Eighth and Ninth Pandemic Waves in Japan After Introducing Regular Rapid Antigen Testing. Preprints 2024, 2024050796. https://doi.org/10.20944/preprints202405.0796.v1 Nagasawa, M.; Kato, T.; Sakaguchi, H.; Tanaka, I.; Watanabe, A.; Hiroshima, Y.; Sakurai, M. Single-Facility Analysis of COVID-19 Status of Healthcare Employee During the Eighth and Ninth Pandemic Waves in Japan After Introducing Regular Rapid Antigen Testing. Preprints 2024, 2024050796. https://doi.org/10.20944/preprints202405.0796.v1

Abstract

Background Community infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have increased rapidly since the emergence of the Omicron strain. During the eighth and ninth pandemic waves—when movement restrictions in the community were eased—the all-case registration system was changed, and the actual status of infection became uncertain. Methods We conducted regular rapid antigen tests (R-RAT) once or twice a week to examine the actual state of coronavirus disease (COVID-19) diagnosis among healthcare employees. Results Overall, 320 (1.42/day) and 299 (1.76/day) employees were infected in the eighth and ninth pandemic waves. During both periods, 59/263 doctors (22.4%), 335/806 nurses (41.6%), 92/194 administrative employees (47.4%), and 129/218 clinical laboratory technicians (59.2%) were infected. In the eighth wave, 56 of 195 employees were infected through close contact; in the ninth wave, 26 of 62 employees were infected. No significant difference was observed in the number of vaccinations between infected and non-infected employees. The positivity rate of R-RAT was 0.41% and 0.45% in the eighth and ninth waves. R-RAT detected infection in 212 and 229 employees during the eighth and ninth waves, respectively; the ratio of R-RAT-detected positive employees to those who reported infection was significantly higher during the ninth wave (odds ratio: 1.67, 95% confidence interval: 1.17–2.37, p

Keywords

COVID-19; Omicron strain; rapid antigen test; healthcare employee; notification system

Subject

Public Health and Healthcare, Public Health and Health Services

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