Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Process Synthesis, Design and Techno-Economic Assessment of Bio-Succinic Acid Production

Version 1 : Received: 6 May 2024 / Approved: 7 May 2024 / Online: 7 May 2024 (10:43:59 CEST)

How to cite: Melitos, G.; Misailidis, N.; Petrides, D.; Georgiadis, M. C. Process Synthesis, Design and Techno-Economic Assessment of Bio-Succinic Acid Production. Preprints 2024, 2024050364. https://doi.org/10.20944/preprints202405.0364.v1 Melitos, G.; Misailidis, N.; Petrides, D.; Georgiadis, M. C. Process Synthesis, Design and Techno-Economic Assessment of Bio-Succinic Acid Production. Preprints 2024, 2024050364. https://doi.org/10.20944/preprints202405.0364.v1

Abstract

This paper investigates the potential of different fermentation feedstocks towards succinic acid production. Three alternative flowsheets were constructed and modelled in SuperPro Designer™, utilizing different fermentation substrates: crude glycerol (a by-product of the biodiesel industry), a commercial 95% glucose syrup and pure glycerol. Techno-economic analysis of the modelled plants showed that all three potential investments can be economically profitable, with the crude glycerol case as the most promising one. The succinic acid production cost for the crude glycerol scenario is estimated at 3.59 $/kg, while a thorough study of the capacity effect to the economics showed that it could drop as low as $2.6 $/kg. Parametric analysis and optimization performed on a flowsheet level, indicated opportunities for lowering the production cost down to 3 $/kg, a value that could pave the framework for a further potential decrease in the selling price of the product.

Keywords

succinic acid; fermentation; bioprocess modelling; techno-economic assessment; optimization

Subject

Engineering, Bioengineering

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