Gill, R.; Al-Badr, M.; Al-Ghouti, M.A.; Mohamed, N.A.; Abou-Saleh, H.; Rahman, M.M. Revolutionizing Cardiovascular Health with Nano-Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Preprints2024, 2024041839. https://doi.org/10.20944/preprints202404.1839.v1
APA Style
Gill, R., Al-Badr, M., Al-Ghouti, M.A., Mohamed, N.A., Abou-Saleh, H., & Rahman, M.M. (2024). Revolutionizing Cardiovascular Health with Nano-Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Preprints. https://doi.org/10.20944/preprints202404.1839.v1
Chicago/Turabian Style
Gill, R., Haissam Abou-Saleh and Md Mizanur Rahman. 2024 "Revolutionizing Cardiovascular Health with Nano-Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach" Preprints. https://doi.org/10.20944/preprints202404.1839.v1
Abstract
Omega-3 polyunsaturated fatty acids (ɷ-3 PUFAs) offer diverse health benefits, such as supporting cardiovascular health, improving cognitive function, promoting joint and musculoskeletal health, and contributing to healthy aging. Despite their advantages, challenges like oxidation susceptibility, low bioavailability, and potential adverse effects at high doses persist. Nanoparticle encapsulation emerges as a promising avenue to address these limitations while preserving stability, enhanced bioavailability, and controlled release. This comprehensive review explores the therapeutic roles of omega-3 fatty acids, critically appraising their shortcomings and delving into modern encapsulation strategies. Furthermore, it explores the potential advantages of Metal-organic framework nanoparticles (MOF NPs) compared to other commonly utilized nanoparticles in improving the therapeutic effectiveness of omega-3 fatty acids within drug delivery systems (DDS). Additionally, it outlines future research directions to fully exploit the therapeutic benefits of these encapsulated omega-3 formulations for cardiovascular disease treatment.
Keywords
Omega-3 fatty acids; cardiovascular disease; Nanoparticle encapsulation; Metal-organic framework; Drug delivery systems
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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