Version 1
: Received: 20 April 2024 / Approved: 22 April 2024 / Online: 23 April 2024 (09:13:21 CEST)
How to cite:
Wu, X.; Ye, L.; Zhang, X.; Yang, X.; Yong-Qiang Hong, Y.; Chiu, W. Clinical Implications of Umbilical Venous Blood Flow to Placental Ratio in Fetal Well-Being. Preprints2024, 2024041479. https://doi.org/10.20944/preprints202404.1479.v1
Wu, X.; Ye, L.; Zhang, X.; Yang, X.; Yong-Qiang Hong, Y.; Chiu, W. Clinical Implications of Umbilical Venous Blood Flow to Placental Ratio in Fetal Well-Being. Preprints 2024, 2024041479. https://doi.org/10.20944/preprints202404.1479.v1
Wu, X.; Ye, L.; Zhang, X.; Yang, X.; Yong-Qiang Hong, Y.; Chiu, W. Clinical Implications of Umbilical Venous Blood Flow to Placental Ratio in Fetal Well-Being. Preprints2024, 2024041479. https://doi.org/10.20944/preprints202404.1479.v1
APA Style
Wu, X., Ye, L., Zhang, X., Yang, X., Yong-Qiang Hong, Y., & Chiu, W. (2024). Clinical Implications of Umbilical Venous Blood Flow to Placental Ratio in Fetal Well-Being. Preprints. https://doi.org/10.20944/preprints202404.1479.v1
Chicago/Turabian Style
Wu, X., Yong-Qiang Yong-Qiang Hong and Wei-Hsiu Chiu. 2024 "Clinical Implications of Umbilical Venous Blood Flow to Placental Ratio in Fetal Well-Being" Preprints. https://doi.org/10.20944/preprints202404.1479.v1
Abstract
Objectives: The purpose of this study is to determine the association between umbilical venous blood flow (UVBF) to placental pulsatility index (PPI) ratio and gestational age (GA) in women undergoing prenatal assessments and adverse pregnancy outcome (APO) screening
Methods: Between January and December 2022, sonographic examinations were conducted to assess the fetal umbilical cord insertion site in singleton fetuses, and hemodynamic indices of the umbilical artery, umbilical vein, and uterine artery were computed. Through regression analysis, we derived the optimal regression equation to elucidate the UVBF/PPI ratio parameters based on GA.
Results: Among 492 singleton fetuses between 21+0 and 40+6 weeks of gestation in the final study. The average fetal UVBF/PPI ratio was 180.45±119.32. Correlation analysis revealed a positive relationship between the UVBF/PPI ratio and GA(p = .000). Using regression analysis, the best-fit regression equation was the linear function model, which explains the value of UVBF/PPI ratio parameters based on GA. Lower UVBF/PPI ratio revealed a positive relationship in the low birth weight fetuses (p=0.021) and higher preterm delivery rate (p=0.034). Cerebroplacental ratio (CPR) showed a high correlation with the UVBF/PPI ratio (r=0.471, p=0.000).
Conclusions: The findings of our analyses revealed that contribute to our understanding of fetal hemodynamics and highlight the potential of UVBF/PPI ratio as a predictive marker for adverse pregnancy outcomes, such as preterm birth, low birth weight, or potential fetal hypoxemia. It might be useful for prenatal counseling and clinical purposes.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
