Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Mindfulness, Gut‐Brain Axis and Health Related Quality of Life: The Paradigm of IBD Patients

Version 1 : Received: 18 April 2024 / Approved: 18 April 2024 / Online: 19 April 2024 (08:19:40 CEST)

How to cite: Christodoulou, E.; Mpali, T.; Dimitriadou, M.; Koutelidakis, A.E. Mindfulness, Gut‐Brain Axis and Health Related Quality of Life: The Paradigm of IBD Patients. Preprints 2024, 2024041293. https://doi.org/10.20944/preprints202404.1293.v1 Christodoulou, E.; Mpali, T.; Dimitriadou, M.; Koutelidakis, A.E. Mindfulness, Gut‐Brain Axis and Health Related Quality of Life: The Paradigm of IBD Patients. Preprints 2024, 2024041293. https://doi.org/10.20944/preprints202404.1293.v1

Abstract

Health-Related Quality of Life (HRQoL) encompasses the comprehensive evaluation of an indi-vidual's health and well-being across multiple dimensions. Mindfulness, recognized as a scientifi-cally supported strategy for anxiety management, plays a role in enhancing both physical and mental health. The Gut-Brain Axis (GBA) serves as the bidirectional communication link between the gastrointestinal system and the central nervous system. This study aims to explore the associa-tion between Mindfulness and factors influencing the GBA in both healthy individuals and those with Inflammatory Bowel Diseases (IBD). A cross-sectional investigation involved 338 adults, in-cluding 50 IBD patients, utilizing validated Greek scales for Mindfulness (MAAS-15), Mediterra-nean Diet (14-MEDAS), and HRQoL (EQ-5D-5L). The questionnaire gathered demographic, an-thropometric, and lifestyle data. Among healthy participants, EQ-5D-5L showed a moderate cor-relation with the MAAS-15 scale (r=0.389, p

Keywords

Mindfulness; gut-brain axis; health related quality of life; inflammatory bowel disease; Mediterranean diet; well-being

Subject

Public Health and Healthcare, Health Policy and Services

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