Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Acute Exercise for the Hypertensive Elderly Affects the Whole-Body Capillary: A Single- Center Pilot Trial

Version 1 : Received: 18 April 2024 / Approved: 18 April 2024 / Online: 18 April 2024 (10:38:35 CEST)

How to cite: Miura, M.; Kohzuki, M.; Saito, C.; Sakai, S.; Sugaya, H.; Koyama, S.; Matsui, Y.; Sakuma, T.; Ito, O.; Yamagata, K. Acute Exercise for the Hypertensive Elderly Affects the Whole-Body Capillary: A Single- Center Pilot Trial. Preprints 2024, 2024041242. https://doi.org/10.20944/preprints202404.1242.v1 Miura, M.; Kohzuki, M.; Saito, C.; Sakai, S.; Sugaya, H.; Koyama, S.; Matsui, Y.; Sakuma, T.; Ito, O.; Yamagata, K. Acute Exercise for the Hypertensive Elderly Affects the Whole-Body Capillary: A Single- Center Pilot Trial. Preprints 2024, 2024041242. https://doi.org/10.20944/preprints202404.1242.v1

Abstract

Objective To investigate nailfold capillary parameters in community-dwelling individuals aged over 60 years who have hypertension and do not exercise regularly. Furthermore, the study examined the correlations between capillary function and other health-related indicators. Design A single- center pilot trial Setting Faculty of Health, Tsukuba University of Technology, Japan Participants hypertensive community-dwelling elderly people Intervention Microcirculation was observed before and 1 min after arm-curl exercise by means microscopy of capillary with non-exercised limb. Additionally, we examined other health-related indicators. Outcome measures: Acute effects of reperfusion on nailfold density, flow, and diameters. Secondary outcomes included the correlations between microvascular parameters and other health-related indicators. We hypothesized that brief exercise could enhance microcirculation reperfusion and correlate with other health-related parameters.  Results: There were 20 participants with a mean (SD) age of 67.1 (5.8) years. The capillary flow rate changed from 2.3±6.7 to 2.7±0.2 log µm/s (P

Keywords

 nailfold capillary; acute exercise; hypertensive elderly; health related parameters 

Subject

Medicine and Pharmacology, Clinical Medicine

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