Live-Birth Incidence of Isolated D-Transposition of Great Arteries – the Shifted Trend Due to Early Diagnosis

Andreea Florentina Stancioi-Cismaru; Marina Dinu; Andreea Carp-Veliscu; Razvan Grigoras Capitanescu; Razvan Cosmin Pana; Ovidiu Costinel Sirbu; Florentina Tanase; Florentina Gratiela Dita; Maria Adelina Popa; Mihai Robert Robu; Mihaela Gheonea; Stefania Tudorache

doi:10.20944/preprints202404.1114.v1

How to cite: Stancioi-Cismaru, A.F.; Dinu, M.; Carp-Veliscu, A.; Capitanescu, R.G.; Pana, R.C.; Sirbu, O.C.; Tanase, F.; Dita, F.G.; Popa, M.A.; Robu, M.R.; Gheonea, M.; Tudorache, S. Live-Birth Incidence of Isolated D-Transposition of Great Arteries – the Shifted Trend Due to Early Diagnosis. Preprints 2024, 2024041114. https://doi.org/10.20944/preprints202404.1114.v1 Stancioi-Cismaru, A.F.; Dinu, M.; Carp-Veliscu, A.; Capitanescu, R.G.; Pana, R.C.; Sirbu, O.C.; Tanase, F.; Dita, F.G.; Popa, M.A.; Robu, M.R.; Gheonea, M.; Tudorache, S. Live-Birth Incidence of Isolated D-Transposition of Great Arteries – the Shifted Trend Due to Early Diagnosis. Preprints 2024, 2024041114. https://doi.org/10.20944/preprints202404.1114.v1

Abstract

This is a single tertiary center in southwest Romania, population-based, study. We retrospectively compared data obtained in two periods: January 2008 - December 2013 and January 2018 - De-cember 2023, respectively. The global incidence of transposition of great arteries (TGA) - the ter-minated cases added to the ones resulting in live-born pregnancies, remained almost constant. The live-born incidence of TGA decreased (0.34% to 0.013%). The prenatal detection rate increased slightly (71.42% to 87.5%). The median gestational age at the diagnosis decreased, from 29.3 ges-tational weeks (mean 25.4) to 13.4 weeks (mean 17.2). The proportion of terminated pregnancies significantly increased (14.28% to 75%, p = 0.019).

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Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Live-Birth Incidence of Isolated D-Transposition of Great Arteries – the Shifted Trend Due to Early Diagnosis

Abstract

Keywords

Subject

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