Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

Chiara Voltan; Francesca Concer; Luca Pecoraro; Angelo Pietrobelli; Giorgio Piacentini; Marco Zaffanello

doi:10.20944/preprints202403.1806.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 28 March 2024 / Approved: 29 March 2024 / Online: 29 March 2024 (09:50:05 CET)

Furthermore, the nasal congestion typical of rhinitis can contribute to upper airway obstruction and sleep-disordered breathing. A vicious circle is created between asthma and sleep-disordered breathing: uncontrolled asthma and sleep-disordered breathing can worsen each other. In children with genetic obesity, despite alterations in the immune system, fewer allergies are found compared to the general population. The causes of this reduced allergenicity are unclear but probably involve genetic, immunological, and environmental factors. Further studies are needed to understand the mechanisms. The study emphasizes the importance of jointly evaluating and managing allergies, obesity, and sleep-disordered breathing in children, considering their close interconnection.

allergy; children; Down Syndrome; inflammation; obesity; obstructive sleep apnoea; Prader-Willi syndrome; sleep-disordered breathing.

Public Health and Healthcare, Public Health and Health Services

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Exploring the Complex Interplay of Obesity, Allergic Diseases, and Sleep-Disordered Breathing In Children

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