Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: a long-term single-center experience.

Version 1 : Received: 28 February 2024 / Approved: 29 February 2024 / Online: 29 February 2024 (09:52:20 CET)

A peer-reviewed article of this Preprint also exists.

Di Michele, S.; Bramante, S.; Angioni, S.; Bernassola, M.; De Vita, T.; Iaccarino, D.A.; Giannoni, L.; Rosati, M. Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: A Long-Term Single-Center Experience. J. Clin. Med. 2024, 13, 1722. Di Michele, S.; Bramante, S.; Angioni, S.; Bernassola, M.; De Vita, T.; Iaccarino, D.A.; Giannoni, L.; Rosati, M. Superficial Peritoneal Endometriosis Vaporization Using a CO2 Laser: A Long-Term Single-Center Experience. J. Clin. Med. 2024, 13, 1722.

Abstract

Background: The validation of laser usage during laparoscopic procedures, notably by Camran Nezhat in the late 1980s, has been significant. Lasers offer precision and depth control in tissue vaporization without bleeding. Surgical intervention remains central in managing endometrio-sis-associated pain and infertility, especially for patients unresponsive to hormonal therapy. Methods: This retrospective cohort study included 200 patients with SPE who underwent laparo-scopic laser vaporization. Surgery was performed using a CO2 laser, and histological confirma-tion of endometriosis was obtained for all cases. Pain scores and SF-36 questionnaire domains were assessed preoperatively and postoperatively. Fertility outcomes were evaluated among pa-tients desiring pregnancy. Results: Significant improvements in pain score and SF-36 questionnaire domains were ob-served postoperatively (p-value

Keywords

endometriosis; superficial peritoneal endometriosis; CO2 laser; pain; fertility

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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