Version 1
: Received: 28 February 2024 / Approved: 29 February 2024 / Online: 29 February 2024 (12:50:13 CET)
How to cite:
Kaur, P.; Darwish, A.G.; El-Sharkawy, I.; Singh, A.; Subramanian, J. Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour-Cherry Cultivars Based on UPLC-TOF-MS. Preprints2024, 2024021706. https://doi.org/10.20944/preprints202402.1706.v1
Kaur, P.; Darwish, A.G.; El-Sharkawy, I.; Singh, A.; Subramanian, J. Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour-Cherry Cultivars Based on UPLC-TOF-MS. Preprints 2024, 2024021706. https://doi.org/10.20944/preprints202402.1706.v1
Kaur, P.; Darwish, A.G.; El-Sharkawy, I.; Singh, A.; Subramanian, J. Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour-Cherry Cultivars Based on UPLC-TOF-MS. Preprints2024, 2024021706. https://doi.org/10.20944/preprints202402.1706.v1
APA Style
Kaur, P., Darwish, A.G., El-Sharkawy, I., Singh, A., & Subramanian, J. (2024). Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour-Cherry Cultivars Based on UPLC-TOF-MS. Preprints. https://doi.org/10.20944/preprints202402.1706.v1
Chicago/Turabian Style
Kaur, P., Ashutosh Singh and Jayasankar Subramanian. 2024 "Comparative Antioxidant Activity and Untargeted Metabolomic Analyses of Sour-Cherry Cultivars Based on UPLC-TOF-MS" Preprints. https://doi.org/10.20944/preprints202402.1706.v1
Abstract
A total of 473 metabolites were identified from 4 sour cherry genotypes using UPLC-TOF-MS. Untargeted metabolomics revealed the dominant chemical groups present in sour cherries. PCA showed that the diversity in sour-cherry metabolites was due to the genotype differences indicating iditol, malic acid, chlorobenzene, 2-mercaptobenzothiazole, and pyroglutamic acid as the predominant contributors. The variable importance in the projection (VIP > 1.0) in partial least-squares–discriminant analysis described 20 biomarker metabolites, representing the cherry metabolome profiles. A heatmap of Pearson’s correlation analysis between the 20 biomarker metabolites and antioxidant activities identified seven antioxidant determinants that displayed the highest correlations with different types of antioxidant activities. This study of correlating metabolomics and antioxidant activities elucidated that the higher nutritional value and biological functions of select sour cherry genotypes can be useful for the development of nutraceutical and functional foods.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
