Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses

Version 1 : Received: 16 February 2024 / Approved: 19 February 2024 / Online: 19 February 2024 (08:22:54 CET)

How to cite: Salzillo, C.; Basile, R.; Cazzato, G.; Ingravallo, G.; Marzullo, A. The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses. Preprints 2024, 2024021022. https://doi.org/10.20944/preprints202402.1022.v1 Salzillo, C.; Basile, R.; Cazzato, G.; Ingravallo, G.; Marzullo, A. The Value of Autopsy in the Modern Age: Discrepancy between Clinical and Autopsy Diagnoses. Preprints 2024, 2024021022. https://doi.org/10.20944/preprints202402.1022.v1

Abstract

Introduction. Autopsy is a medical procedure that consists of the corpse’s examination to determine the cause of death and obtain information on pathological conditions or injuries present in the body. In recent years there has been a reduction in hospital autopsies and an increase in forensic autopsies. Material and methods. A retrospective observational study was conducted on the reports of all the 645 hospital autopsies performed at Polyclinic of Bari from 2006 to 2021.Results. Group A, 2006-2009, 174 cases were studied: 58% male, 58% adults, 55% neonatology, pulmonary disease was the cause of death in 23%, and 55% of discrepancy between clinical and autopsy diagnosis. Group B, 2010-2013, comprised 119 cases: 52% male, 46% infants, 48% neonatology, pulmonary disease was the cause of death in 25%, and 56% of discrepancy between clinical and autopsy diagnosis. Group C, 2014-2017, comprised 168 cases: gender equality, 37% infants, 25% gynecology, pulmonary disease was the cause of death in 24%, and 58% of discrepancy between clinical and autopsy diagnosis. Group D, 2018-2021 comprised 184 cases: 56% male, 38% adult, 32% gynecology, pulmonary disease was the cause of death in 27%, and 58% discrepancy between clinical and autopsy diagnosis.Conclusion. The study of hospital autopsies at the Polyclinic of Bari shows that the discrepancy between clinical and autopsy diagnosis is around 56.75%. Thus, the hospital autopsy is helpful in the modern age, especially for diagnosing fetal and neonatal diseases.

Keywords

hospital autopsy; modern age; clinical diagnosis; autopsy diagnosis; Public Health

Subject

Medicine and Pharmacology, Pathology and Pathobiology

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