Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Divergences in Antiviral Therapy for Diabetic Patients with COVID-19

Andreea Fitero
,
Nicoleta Negrut
* ORCID logo ,
Carmen Delia Nistor-Cseppento
* ,
Delia Mirela Tit
ORCID logo ,
Paul Andrei Negru
ORCID logo ,
Cristian Bustea
,
Andrei-Flavius Radu
ORCID logo ,
Simona Gabriela Bungau
Version 1 : Received: 6 February 2024 / Approved: 7 February 2024 / Online: 7 February 2024 (07:57:47 CET)

A peer-reviewed article of this Preprint also exists.

Fitero, A.; Negruț, N.; Cseppento, D.C.N.; Tit, D.M.; Negru, P.A.; Bustea, C.; Radu, A.F.; Bungau, S.G. Divergences in Antiviral Therapy for Diabetic Patients with COVID-19. Pharmacophore 2024, 15, 79–89, doi:10.51847/perpvy0am7. Fitero, A.; Negruț, N.; Cseppento, D.C.N.; Tit, D.M.; Negru, P.A.; Bustea, C.; Radu, A.F.; Bungau, S.G. Divergences in Antiviral Therapy for Diabetic Patients with COVID-19. Pharmacophore 2024, 15, 79–89, doi:10.51847/perpvy0am7.

Abstract

Abstract: Background: Patients with diabetes are particularly susceptible to COVID-19 infection, which can result in severe respiratory illness. Methods: This study conducted a comparative as-sessment of the impact of antiviral therapy using molnupiravir and favipiravir in COVID-19 pa-tients with underlying diabetes. A cohort of one hundred individuals infected with SARS-CoV-2, diagnosed with diabetes, and consecutively admitted, was included in the present study. These patients were treated with antivirals according to local guidelines: Group F (51 cases) was treated with favipiravir – 10 days and Group M (49 cases) was treated with molnupiravir – 5 days. Re-sults: In Group F, the average hospitalization was higher than in Group M (11.29±2.27 vs. 7.14±3.16, p

Keywords

SARS-CoV-2; favipiravir; molnupiravir; diabetes mellitus; COVID-19

Subject

Medicine and Pharmacology, Clinical Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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