Version 1
: Received: 4 February 2024 / Approved: 5 February 2024 / Online: 5 February 2024 (11:05:18 CET)
How to cite:
Petleshkova, P.V.; Krasteva, M.B.; Pacheva, I.H.; Dragusheva, S.S.; Ruseva, M.L. Title Arnica D30 – an Alternative for Managing Procedural Pain in Full-Term Neonates. Preprints2024, 2024020231. https://doi.org/10.20944/preprints202402.0231.v1
Petleshkova, P.V.; Krasteva, M.B.; Pacheva, I.H.; Dragusheva, S.S.; Ruseva, M.L. Title Arnica D30 – an Alternative for Managing Procedural Pain in Full-Term Neonates. Preprints 2024, 2024020231. https://doi.org/10.20944/preprints202402.0231.v1
Petleshkova, P.V.; Krasteva, M.B.; Pacheva, I.H.; Dragusheva, S.S.; Ruseva, M.L. Title Arnica D30 – an Alternative for Managing Procedural Pain in Full-Term Neonates. Preprints2024, 2024020231. https://doi.org/10.20944/preprints202402.0231.v1
APA Style
Petleshkova, P.V., Krasteva, M.B., Pacheva, I.H., Dragusheva, S.S., & Ruseva, M.L. (2024). Title Arnica D30 – an Alternative for Managing Procedural Pain in Full-Term Neonates. Preprints. https://doi.org/10.20944/preprints202402.0231.v1
Chicago/Turabian Style
Petleshkova, P.V., Snezhana Stefanova Dragusheva and Margarita Lyubenova Ruseva. 2024 "Title Arnica D30 – an Alternative for Managing Procedural Pain in Full-Term Neonates" Preprints. https://doi.org/10.20944/preprints202402.0231.v1
Abstract
Background: Despite scientific advances, the management of procedural pain in neonates remains suboptimal. Applying adequate therapy to control pain during the neonatal period is a moral and ethical act. In recent decades, ample evidence has accumulated regarding the risks, associated with both untreated pain and the use of more aggressive analgesic therapy. Thus, the emphasis in neonatal clinical practice is on non-aggressive pain management techniques, including homeopathic agents. The efficacy and safety of homeopathic agents for reducing procedural pain in neonates is the subject of the present study. Materials and Methods: Healthy full-term newborn babies with an average age of 72-84 hours were included. They were divided into three study groups: group (A) – not anesthetised, /n= 67/, group (B) – anesthetised with Arnica D30 /n=40/ and group (C)- anesthetised with Sol.Glucose 25% /n=40/. The severity of the pain was assessed using the multimodal - Neonatal Infant Pain Scale (NIPS) and the unimodal - Neonatal Facial Coding System (NFCS) scale. Assessments were done 30s before, 30 seconds after, and 5 minutes after the painful stimulus caused by the heel prick. Heart rate, transcutaneous oxygen saturation, respiratory rate and blood pressure were examined at the same intervals. The results obtained were processed statistically by descriptive analysis and ANOVA at a significance level of p< 0.05. Results: 5 minutes after heel prick both scales showed a statistically significant lower score in those given Arnica D30, compared to those who received Sol.Glucose 25%. When monitoring the physiological indicators, we found a significant increase in the heart rate 30 seconds after the procedure.5 minutes after the heel prick we recorded significantly respiratory rate and systolic blood pressure in all three groups compared to pre-procedural values. Conclusions: Arnica D30 has better analgesic effects compared to Sol.Glucose 25% for newborn babies after heel prick tests.
Medicine and Pharmacology, Pediatrics, Perinatology and Child Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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