Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease Following Sleeve Gastrectomy

Version 1 : Received: 18 January 2024 / Approved: 19 January 2024 / Online: 19 January 2024 (10:49:23 CET)

A peer-reviewed article of this Preprint also exists.

Masood, M.; Low, D.E.; Deal, S.B.; Kozarek, R.A. Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy. J. Clin. Med. 2024, 13, 1246. Masood, M.; Low, D.E.; Deal, S.B.; Kozarek, R.A. Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy. J. Clin. Med. 2024, 13, 1246.

Abstract

Obesity is associated with serious comorbidities and economic implications. Bariatric surgery, most commonly Roux-en-Y gastric bypass and sleeve gastrectomy, are effective options for weight loss and improvement of obesity-related comorbidities. With the growing obesity epidemic, there has been a concomitant rise in bariatric surgeries, particularly in sleeve gastrectomy, which has been the most widely performed bariatric surgery since 2013. Gastroesophageal reflux disease (GERD) is highly prevalent in obese individuals, can significantly impact quality of life and may lead to serious complications. Obesity and GERD both improve with weight loss. However, as the incidence of sleeve gastrectomy rises, recent data has revealed a risk of exacerbation of pre-existing GERD or the development of de novo GERD following sleeve gastrectomy. We performed a detailed review of GERD post-sleeve gastrectomy, including its overall incidence, pathophysiology and current treatment paradigms.

Keywords

Gastroesophageal, reflux; GERD, esophagitis, morbid, obesity, bariatric, gastric, sleeve, gastrectomy

Subject

Public Health and Healthcare, Primary Health Care

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