Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Latest Trends in Hemodiafiltration

Version 1 : Received: 12 January 2024 / Approved: 15 January 2024 / Online: 15 January 2024 (10:26:34 CET)

A peer-reviewed article of this Preprint also exists.

Maduell, F.; Rodríguez-Espinosa, D.; Broseta, J.J. Latest Trends in Hemodiafiltration. J. Clin. Med. 2024, 13, 1110. Maduell, F.; Rodríguez-Espinosa, D.; Broseta, J.J. Latest Trends in Hemodiafiltration. J. Clin. Med. 2024, 13, 1110.

Abstract

This review provides a detailed analysis of hemodiafiltration (HDF), its progress from an emerging technique to a potential conventional treatment for chronic hemodialysis patients, and its current status. The article covers advances, methodologies, and clinical benefits of HDF, spe-cifically focusing on its impact on cardiovascular health, survival rates, and overall well-being. The text also addresses concerns about the safety of HDF and provides evidence to dispel worries re-lated to the elimination of beneficial substances and infection risks. Additionally, the article ex-plores the potential implications of expanded hemodialysis (HDx) as an alternative to HDF, its classification, safety profile, and an ongoing trial assessing its non-inferiority to HDF. Supported by evidence from randomized controlled trials and observational studies, the review emphasizes the superiority of HDF as a hemodialysis modality, advocating for its positioning as the gold standard in treatment. However, it acknowledges the need for extensive research to define the role of HDx in comprehensive treatment approaches for individuals undergoing dialysis. The synthesis of current knowledge underscores the importance of ongoing exploration and research to refine hemodialysis practices for optimal patient outcomes.

Keywords

Hemodiafiltration; Dialyzer compatibility; survival; safety

Subject

Medicine and Pharmacology, Urology and Nephrology

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