Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Comparative Antifungal Activity of Commercial Probiotics against Candida albicans – an Invitro Study

Version 1 : Received: 8 January 2024 / Approved: 9 January 2024 / Online: 9 January 2024 (10:32:31 CET)

How to cite: Srinivasan, M.; Syam, S. Comparative Antifungal Activity of Commercial Probiotics against Candida albicans – an Invitro Study. Preprints 2024, 2024010667. https://doi.org/10.20944/preprints202401.0667.v1 Srinivasan, M.; Syam, S. Comparative Antifungal Activity of Commercial Probiotics against Candida albicans – an Invitro Study. Preprints 2024, 2024010667. https://doi.org/10.20944/preprints202401.0667.v1

Abstract

Background : Probiotics are composed of microorganisms that have positive effects on health when consumed in prescribed quantities. Lately, studies have attempted to establish this role of probiotics in enhancing health. Aim : The aim of this study was to compare the antifungal activity of 3 different probiotics against Candida albicans.Methodology :This was an in-vitro study. 3 types of commercially available probiotics - Bifilac, Pre pro HS and VSL-3 were cultured separately with Candida albicans and were placed under incubation. The maximum zone of inhibition was recorded for each of the probiotic solutions.Results : In this study, it was found that among the three probiotic products, Bifilac exhibited a maximum zone of inhibition of 13mm at concentration of 100µL against C. albicans, while Pre pro HS and VSL-3 showed zone of inhibition of 11mm at concentrations of 50µL and 100µL, respectively.Conclusion : Within the limits of the present study, This study could prove that probiotics can be considered as an alternative and safe treatment option for treatment of Oral candidiasis infections.

Keywords

Antimicrobial; Yeast; In vitro; Sabouraud Dextrose Agar; Culture; Infection

Subject

Biology and Life Sciences, Immunology and Microbiology

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