Version 1
: Received: 6 January 2024 / Approved: 8 January 2024 / Online: 8 January 2024 (09:41:28 CET)
How to cite:
Levin, M. Superior Mesenteric Artery Syndrome Results From Hypersecretion of Hydrochloric Acid. Preprints2024, 2024010605. https://doi.org/10.20944/preprints202401.0605.v1
Levin, M. Superior Mesenteric Artery Syndrome Results From Hypersecretion of Hydrochloric Acid. Preprints 2024, 2024010605. https://doi.org/10.20944/preprints202401.0605.v1
Levin, M. Superior Mesenteric Artery Syndrome Results From Hypersecretion of Hydrochloric Acid. Preprints2024, 2024010605. https://doi.org/10.20944/preprints202401.0605.v1
APA Style
Levin, M. (2024). Superior Mesenteric Artery Syndrome Results From Hypersecretion of Hydrochloric Acid. Preprints. https://doi.org/10.20944/preprints202401.0605.v1
Chicago/Turabian Style
Levin, M. 2024 "Superior Mesenteric Artery Syndrome Results From Hypersecretion of Hydrochloric Acid" Preprints. https://doi.org/10.20944/preprints202401.0605.v1
Abstract
It is currently believed that the cause of superior mesenteric artery syndrome (SMAS) is compression of the duodenum in the angle between the aorta and superior mesenteric artery (SMA). It is recognized that a decrease in aortomesenteric angle (AMA) <25° and intervascular distance < 8 mm, caused by fat loss, is characteristic of SMAS. Based on these statements, surgeons operate on patients with symptoms of dyspepsia only based on a reduction of AMA. This study is devoted to the analysis of the literature, including four own studies on this issue. Results: Measurement of the length of the constriction in the third part of the duodenum on radiograms from available sources showed that its true length ranged from 2.5 to 4.2 (3.30±0.15) cm and began a few centimeters cranial to the AMA. Therefore, it could not have been caused by compression in the AMA. In terms of length (3.20±0.15 cm) and location, this constriction corresponded to Ochsner’s sphincter, which normally short-term contracts to prevent the penetration of an acid bolus into the jejunum. Conscientious studies have shown that AMA is proportional to BMI, i.e., a decrease in AMA is observed in all thin people. An analysis of 211 cases of SMAS made it possible to differentiate two types of diseases. In 101 patients, the disease occurred acutely 1–53 (8.2 ± 1.9) days after stressful situations, accompanied by a catabolic reaction and hypersecretion of hydrochloric acid. In 110 patients, SMAS developed 3-72 (17.2±3.2) months after the diagnosis of acid-dependent diseases. Conclusion: The analysis of the literature led to the conclusion that hypersecretion of hydrochloric acid causes damage to the upper level of the digestive system, including duodenal dyskinesia. One of the manifestations of duodenal dyskinesia is an increase in tone and hypertrophy of the Ochsner’s sphincter. The clinic of the disease depends on the varying degree of Ochsner’s sphincter dyskinesia. In severe cases, partial or complete intestinal obstruction. New ideas about the etiology and pathogenesis of the so-called SMAS have made it possible to propose a tactic for the diagnosis and treatment of Ochsner’s sphincter dyskinesia, where there is no place for surgical treatment.
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
