Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Clinical Findings of Listeria monocytogenes Infections with a Special Focus on Bone Localizations

Version 1 : Received: 13 December 2023 / Approved: 13 December 2023 / Online: 13 December 2023 (11:00:12 CET)

A peer-reviewed article of this Preprint also exists.

Bongiovanni, M.; Cavallo, C.; Barda, B.; Strulak, L.; Bernasconi, E.; Cardia, A. Clinical Findings of Listeria monocytogenes Infections with a Special Focus on Bone Localizations. Microorganisms 2024, 12, 178. Bongiovanni, M.; Cavallo, C.; Barda, B.; Strulak, L.; Bernasconi, E.; Cardia, A. Clinical Findings of Listeria monocytogenes Infections with a Special Focus on Bone Localizations. Microorganisms 2024, 12, 178.

Abstract

Listeria monocytogenes is a Gram-positive pathogenic bacterium which can be found in soil or water. Infection with the microorganism can occur after ingestion of contaminated food products. Small and large outbreaks of listeriosis have been described in the past. L. monocytogenes can cause a number of different clinical syndromes, most frequently sepsis, meningitis, and rhombencephalitis, particularly in immunocompromised hosts. L. monocytogenes systemic infections can develop following tissue penetration across the gastrointestinal tract or to hematogenous spread to sterile sites, possibly evolving towards bacteremia. L. monocytogenes only rarely causes bone or joint infections, usually in the context of prosthetic material that can provide a site for bacterial seeding. We describe here the clinical findings of invasive listeriosis, mainly focusing on diagnosis, clinical management and treatment of bone and vertebral infections occurring in the context of invasive listeriosis.

Keywords

Listeria monocytogenes, bone infections

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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