Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Review of the Brain Behaviour after Injury and Disease for Its Application in an Agent Based Model (ABM)

Version 1 : Received: 5 December 2023 / Approved: 7 December 2023 / Online: 7 December 2023 (16:39:47 CET)

How to cite: Irastorza Varela, L.; Benítez Baena, J.M.; Montans, F.; Saucedo-Mora, L. Review of the Brain Behaviour after Injury and Disease for Its Application in an Agent Based Model (ABM). Preprints 2023, 2023120489. https://doi.org/10.20944/preprints202312.0489.v1 Irastorza Varela, L.; Benítez Baena, J.M.; Montans, F.; Saucedo-Mora, L. Review of the Brain Behaviour after Injury and Disease for Its Application in an Agent Based Model (ABM). Preprints 2023, 2023120489. https://doi.org/10.20944/preprints202312.0489.v1

Abstract

The brain being arguably the most complex organ in the human body, its detailed functioning is yet to be fully deciphered, let alone accurately modeled. Nonetheless, the medical community has gathered quite a remarkable amount of studies about the consequences of illnesses and injuries on its development and functioning. This bibliographic review aims to cover mostly the findings related to the changes in the physical distribution of neurons and their connections - the connectome -, both structural and functional, as well as their modelling. It does not intend to offer an extensive medical description of all injuries and diseases affecting the brain, rather presenting the most common ones succinctly so the need for accurate brain modelling can be fully understood and pondered, offering propositions to this aim.

Keywords

Connectome; Brain Injury; Neurodegenerative Diseases; Parkinson; Alzheimer; Dislexia

Subject

Engineering, Bioengineering

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.