Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Colorectal Cancer Liver Metastasis – State of the Art and Future Perspectives

Version 1 : Received: 8 November 2023 / Approved: 8 November 2023 / Online: 8 November 2023 (14:43:44 CET)

A peer-reviewed article of this Preprint also exists.

Ruivo, A.; Oliveira, R.C.; Silva-Vaz, P.; Tralhão, J.G. Colorectal Cancer Liver Metastasis—State-of-the-Art and Future Perspectives. Gastrointest. Disord. 2023, 5, 580-608. Ruivo, A.; Oliveira, R.C.; Silva-Vaz, P.; Tralhão, J.G. Colorectal Cancer Liver Metastasis—State-of-the-Art and Future Perspectives. Gastrointest. Disord. 2023, 5, 580-608.

Abstract

The current management of colorectal cancer liver metastasis (CRCLM) patients involves a multidisciplinary approach with surgical resection remaining the primary curative option. The advances in liver surgery have improved outcomes, enabling more patients to undergo surgery successfully. In addition, the development of imaging software has improved the preoperative planning and patient selection for surgery and other interventions. Systemic therapies, such as targeted therapies and immunotherapies have enhanced the chances of complete resection. Targeted agents in combination with chemotherapy, have shown efficacy in downstaging tumors and increasing resectability.

Keywords

Colon cancer; metastasis; Liver Neoplasms; Review Literature

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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