Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Laparoscopic Prediction of Primary Cytoreducibility of Epithelial Ovarian Cancer

Version 1 : Received: 25 October 2023 / Approved: 26 October 2023 / Online: 26 October 2023 (10:12:52 CEST)

How to cite: Golia D’Augè, T.; Giannini, A.; Cuccu, I.; De Angelis, E.; Di Donato, V.; Muzii, L.; D'Oria, O.; Chiantera, V.; Gerli, S.; Caserta, D.; Besharat, A.R.; Laganà, A.S.; Bogani, G.; Favilli, A. Laparoscopic Prediction of Primary Cytoreducibility of Epithelial Ovarian Cancer. Preprints 2023, 2023101680. https://doi.org/10.20944/preprints202310.1680.v1 Golia D’Augè, T.; Giannini, A.; Cuccu, I.; De Angelis, E.; Di Donato, V.; Muzii, L.; D'Oria, O.; Chiantera, V.; Gerli, S.; Caserta, D.; Besharat, A.R.; Laganà, A.S.; Bogani, G.; Favilli, A. Laparoscopic Prediction of Primary Cytoreducibility of Epithelial Ovarian Cancer. Preprints 2023, 2023101680. https://doi.org/10.20944/preprints202310.1680.v1

Abstract

Ovarian cancer affects thousands of women every year and represents the female cancer with the highest mortality rate. Surgery is currently the cornerstone of the treatment of this disease and several methods have been analyzed and developed to predict the possibility of obtaining a residual tumor of 0 (RT=0). The aim of this review is to analyze the data available in the literature about minimally invasive surgical methods to predict the optimal cytoreduction of patients with advanced epithelial ovarian cancer undergoing primary debulking surgery (PDS). A review of the literature has been performed on the available data about the criteria of cytoreducibility during PDS for the surgical treatment of advanced epithelial ovarian cancer. The assessment of the extent of intra and extrabdominal pathology is essential to guide the surgeon in the most appropriate therapeutic choice for patients with ovarian cancer, so radiological methods (MRI, PET-scan and CT), surgical (mini-laparotomy, laparoscopy) and serological (CA-125, HE4) can provide a huge help for tailoring the therapeutic approach of these patients.

Keywords

ovarian cancer; gynecologic oncology; gynecologic surgery; debulking surgery; PDS; laparoscopy

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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