Version 1
: Received: 22 October 2023 / Approved: 23 October 2023 / Online: 23 October 2023 (09:42:29 CEST)
How to cite:
Mukherjee, S.; Munshi, C. A Mechanistic Discussion on Oxidative Stress and Ferroptosis. Preprints2023, 2023101423. https://doi.org/10.20944/preprints202310.1423.v1
Mukherjee, S.; Munshi, C. A Mechanistic Discussion on Oxidative Stress and Ferroptosis. Preprints 2023, 2023101423. https://doi.org/10.20944/preprints202310.1423.v1
Mukherjee, S.; Munshi, C. A Mechanistic Discussion on Oxidative Stress and Ferroptosis. Preprints2023, 2023101423. https://doi.org/10.20944/preprints202310.1423.v1
APA Style
Mukherjee, S., & Munshi, C. (2023). A Mechanistic Discussion on Oxidative Stress and Ferroptosis. Preprints. https://doi.org/10.20944/preprints202310.1423.v1
Chicago/Turabian Style
Mukherjee, S. and Chayan Munshi. 2023 "A Mechanistic Discussion on Oxidative Stress and Ferroptosis" Preprints. https://doi.org/10.20944/preprints202310.1423.v1
Abstract
Ferroptosis is a recent form of non-apoptotic cell death, which occurs due to imbalance of iron homeostasis (iron overload). Oxidative stress due to the impairment of the antioxidant system is a major pathophysiology during ferroptosis, which eventually results in lipid peroxidation. The cellular and physiological biomarker of ferroptotic cell death includes major alteration in the glutathione peroxidase 4 (GPX4) antioxidant system and lipid peroxidation induced loss of plasma membrane integrity. This review elaborates the mechanism of oxidative stress which triggers ferroptosis.
Biology and Life Sciences, Cell and Developmental Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
