Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Obesity Effect On The Respiratory Parameters In Osas Children

Version 1 : Received: 2 October 2023 / Approved: 2 October 2023 / Online: 3 October 2023 (08:16:58 CEST)

A peer-reviewed article of this Preprint also exists.

Caliendo, C.; Femiano, R.; Umano, G.R.; Martina, S.; Nucci, L.; Perillo, L.; Grassia, V. Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome. Children 2023, 10, 1874. Caliendo, C.; Femiano, R.; Umano, G.R.; Martina, S.; Nucci, L.; Perillo, L.; Grassia, V. Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome. Children 2023, 10, 1874.

Abstract

A Pediatric Sleep Questionnaire (PSQ) and a recording of the respiratory parameters with a noc-turnal home cardiorespiratory polygraphy (PG) are necessary to diagnose OSAS. Few researchers have studied how obesity could influence the respiratory parameters in OSAS children. The aim of the study was to investigate how obesity can influence sleep respiratory parameters in OSAS children. Methods: The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI> 5th percentiles and PSQ value of 0.33. Children were divided into the Obesity Group (OG) with a BMI of  95th and the Control Group (CG) with a 5th<BMI> 95th percentile. All selected children underwent PG. Respiratory parameters were extracted to divide into levels of severity OSAS: snoring, mild, moderate, and severe. Results: The comparison analysis of AHI, SaO2, and Nadir between the OG and CG showed a statistical significance only for ODI (p = 0.02). The comparison analysis of PSQ between the OG and CG and of PSQ and respiratory parameters showed no significant result. A statistically significant correlation between BMI and AHI (r2=0.01), SaO2 (r2=0.09), and Nadir O2 (r2=0.00) was found. Conclusion: There was no strong correlation between Obesity and OSAS, but it was found between BMI increasing and AHI severity

Keywords

Obstructive Sleep Apnea Syndrome (OSAS); Nocturnal Home Cardiorespiratory Polygraphy (PG); Obesity; Saturation O2 (Sa02); Pediatric Sleep Questionnaire (PSQ)

Subject

Biology and Life Sciences, Life Sciences

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