Version 1
: Received: 20 September 2023 / Approved: 21 September 2023 / Online: 22 September 2023 (09:58:09 CEST)
How to cite:
Bachega, F.S.; Baracat, M.C.P.; Simões, R.S.; Maciel, G.A.R.; Lobo, R.A.; Jr, J.M.S.; Baracat, E.C. New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis. Preprints2023, 2023091520. https://doi.org/10.20944/preprints202309.1520.v1
Bachega, F.S.; Baracat, M.C.P.; Simões, R.S.; Maciel, G.A.R.; Lobo, R.A.; Jr, J.M.S.; Baracat, E.C. New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis. Preprints 2023, 2023091520. https://doi.org/10.20944/preprints202309.1520.v1
Bachega, F.S.; Baracat, M.C.P.; Simões, R.S.; Maciel, G.A.R.; Lobo, R.A.; Jr, J.M.S.; Baracat, E.C. New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis. Preprints2023, 2023091520. https://doi.org/10.20944/preprints202309.1520.v1
APA Style
Bachega, F.S., Baracat, M.C.P., Simões, R.S., Maciel, G.A.R., Lobo, R.A., Jr, J.M.S., & Baracat, E.C. (2023). New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis. Preprints. https://doi.org/10.20944/preprints202309.1520.v1
Chicago/Turabian Style
Bachega, F.S., José Maria Soares Jr and Edmund Chada Baracat. 2023 "New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis" Preprints. https://doi.org/10.20944/preprints202309.1520.v1
Abstract
Polycystic ovary syndrome (PCOS) is a prevalent condition characterized by manifestations that can influence self-image and potentially result in psychological distress; however, data from literature on sexual function (SF) in PCOS women are contradictory. We aimed to evaluate sexual dysfunction (SD) in PCOS women by carrying out a systematic review and meta-analysis, using the gold-standard assessment tool SD-diagnosis (Female Sexual Function Index:FSFI). Seven databases were analyzed until August-2023; study quality was assessed by risk of bias and Newcastle Ottawa Scale. Our analysis encompassed 25 case-control studies (9933 women). PCOS group presented significantly lower scores in arousal (MD= -0.36 CI95%-0.60;-0.11), lubrication (MD= -0.52 CI95%-0.75;-0.28), orgasm (MD= -0.39 CI95%-0.57;-0.20), satisfaction (MD= -0.32 CI95%-0.50;-0.14) and pain subdomains (MD= -0.46 CI95%-0.75;-0.16), as in overall FSFI score (MD= -2.27 CI95%-3.23;-1.31). Overweight/obese (OW/O) patients exhibited significantly higher overall FSFI than OW/O controls (MD=1.98 CI95%0.68;3.27), particularly in lubrication (MD= -0.34), orgasm (MD= -0.26) and satisfaction (MD= -0.25) subdomains. These findings offer insights regarding SD in PCOS women and emphasize the need to incorporate SF assessment into multidisciplinary care. By this way, PCOS can be also considered a gateway diagnosis to other long-term consequences. Further research should focus on controlling variables, as ethnicity, culture, religion and economic disparities.
Keywords
Stein-Leventhal Syndrome; Polycystic Ovary Syndrome; Sexuality; Sexual Activity; Sexual Dysfunction; Female Sexual Function Index; Sexual Function; Sexual Disorders; Sexual Behavior; Meta-analysis.
Subject
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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