Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery: Results from a Comparative Study

Tommaso Cai
* ORCID logo ,
Marco Capece
ORCID logo ,
Carlo Ceruti
,
Daniele Tiscione
,
Marco Puglisi
,
Paolo Verze
,
Paolo Gontero
,
Alessandro Palmieri
Version 1 : Received: 5 September 2023 / Approved: 7 September 2023 / Online: 8 September 2023 (02:41:27 CEST)

A peer-reviewed article of this Preprint also exists.

Cai, T.; Capece, M.; Ceruti, C.; Tiscione, D.; Puglisi, M.; Verze, P.; Gontero, P.; Palmieri, A. The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie’s Disease: Results from a Comparative Study. Clin. Pract. 2023, 13, 1244-1252. Cai, T.; Capece, M.; Ceruti, C.; Tiscione, D.; Puglisi, M.; Verze, P.; Gontero, P.; Palmieri, A. The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie’s Disease: Results from a Comparative Study. Clin. Pract. 2023, 13, 1244-1252.

Abstract

Background: Peyronie’s disease (PD) represents a challenging urological disease, due to not optimal post-operative surgical outcomes. We aim to evaluate if vacuum erection devices (VED) treatment before pe-nile curvature surgery is able to improve the post-operative surgical outcomes. Methods: All enrolled patients were assigned to the following groups: a) treatment group, VED treatment (3 times per week) starting 3 months before surgery and (3 times per week) one months after surgery and b) control group, VED treatment (3 times per week) one months after surgery. Follow-up urologic visits were scheduled at 3 and 6 months after surgery and the two groups were compared. Results: Thirty-eight patients have been enrolled (median age 67 years, 57-74, IQR), 20 in the treatment group and 18 in the control group. At the follow-up visits, the two groups are different in terms of IIEF-5 (26 vs 24; p=0.02), ‘yes’ to SEP2 and 3 (85% vs 55%; p<0.001, 85% vs 50%; p<0.001, respectively) and PDQ (-16 vs -11; p=0.03). Complete correction of penile curvature was achieved in 36 patients (94.7%). In the treatment group, no hourglass deformity has been reported, while in the control group 1 patient reported a mild hourglass deformity. In the treatment group, we obtained a longer total penile length (median +1.5 cm). The overall satisfaction rate was 98% in the treatment group and 96% in the control group. Conclusions: The VED treatment before penile curvature surgery in patients affected by PD is able to improve the post-operative surgery.

Keywords

Peyronie's Disease; vacuum erection devices; penile curvature; surgery; quality of life

Subject

Medicine and Pharmacology, Urology and Nephrology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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