Kawase, M.; Shibata, T.; Masuu, S.; Yamaguchi, M.; Matsumura, Y.; Shimomura, O.; Ohtaka, A. Expression of Reaction Selectivity and the Substituent Effect in Ullmann, Suzuki, Hiyama, and Allylic Arylation Reactions Caused by Reducing Catalyst Loading. Catalysts2023, 13, 1115.
Kawase, M.; Shibata, T.; Masuu, S.; Yamaguchi, M.; Matsumura, Y.; Shimomura, O.; Ohtaka, A. Expression of Reaction Selectivity and the Substituent Effect in Ullmann, Suzuki, Hiyama, and Allylic Arylation Reactions Caused by Reducing Catalyst Loading. Catalysts 2023, 13, 1115.
Kawase, M.; Shibata, T.; Masuu, S.; Yamaguchi, M.; Matsumura, Y.; Shimomura, O.; Ohtaka, A. Expression of Reaction Selectivity and the Substituent Effect in Ullmann, Suzuki, Hiyama, and Allylic Arylation Reactions Caused by Reducing Catalyst Loading. Catalysts2023, 13, 1115.
Kawase, M.; Shibata, T.; Masuu, S.; Yamaguchi, M.; Matsumura, Y.; Shimomura, O.; Ohtaka, A. Expression of Reaction Selectivity and the Substituent Effect in Ullmann, Suzuki, Hiyama, and Allylic Arylation Reactions Caused by Reducing Catalyst Loading. Catalysts 2023, 13, 1115.
Abstract
The control of stereo-, regio-, and chemo-selectivity in transition-metal-catalyzed coupling reactions is a key topic in organic synthesis. Several methods for controlling selectivity have been reported thus far. On the other hand, the reduction of the catalyst loading in the reaction is one of the most important issues in organic synthesis from the standpoint of green sustainable chemistry. As another advantage of reducing the catalyst loading, the expression of the reaction selectivity and the substituent effect caused by the reduction of the catalyst loading to the parts-par-million (ppm) level in various catalytic reactions is presented herein.
Keywords
selectivity control; catalyst loading; ppm
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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