Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Sex, Age, and Regional Disparities in the Burden of Asthma in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019

Ana Lopez-Bago
,
Ricardo Lascurain
* ,
Pavel E. Hernandez-Carreño
,
Francisco Gallardo-Vera
,
Jesus Argueta-Donohue
ORCID logo ,
Francisco Jimenez-Trejo
,
David A. Fuentes-Zavaleta
,
Saul A. Beltran-Ontiveros
ORCID logo ,
Delia M. Becerril-Camacho
,
Victor A. Contreras-Rodriguez
,
Daniel Diaz
* ORCID logo
Version 1 : Received: 19 June 2023 / Approved: 20 June 2023 / Online: 21 June 2023 (08:52:17 CEST)

A peer-reviewed article of this Preprint also exists.

Lopez-Bago, A.; Lascurain, R.; Hernandez-Carreño, P.E.; Gallardo-Vera, F.; Argueta-Donohue, J.; Jimenez-Trejo, F.; Fuentes-Zavaleta, D.A.; Beltran-Ontiveros, S.A.; Becerril-Camacho, D.M.; Contreras-Rodriguez, V.A.; Diaz, D. Sex, Age, and Regional Disparities in the Burden of Asthma in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019. Sustainability 2023, 15, 12599. Lopez-Bago, A.; Lascurain, R.; Hernandez-Carreño, P.E.; Gallardo-Vera, F.; Argueta-Donohue, J.; Jimenez-Trejo, F.; Fuentes-Zavaleta, D.A.; Beltran-Ontiveros, S.A.; Becerril-Camacho, D.M.; Contreras-Rodriguez, V.A.; Diaz, D. Sex, Age, and Regional Disparities in the Burden of Asthma in Mexico from 1990 to 2019: A Secondary Analysis of the Global Burden of Disease Study 2019. Sustainability 2023, 15, 12599.

Abstract

Asthma is the most prevalent cause of chronic respiratory diseases. Herein, we evaluate asthma burden in Mexico based on results from the Global Burden of Disease (GBD 2019) study 2019. Using data from the GBD 2019, we estimated asthma prevalence, incidence, mortality, and disability-adjusted lived years (DALYs) counts and crude and age-standardized rates per 100,000 people with a 95% uncertainty interval (UI) by sex and age at the national and subnational levels in Mexico from 1990 to 2019. At the national level, asthma affected 3.35 million (95% UI, 2.59-4.37) people, with 606.0 thousand (433.0-811.1) new incident cases and 1,655 (3-1,931) deaths during 2019. Asthma caused a slightly higher burden in females and affected mainly age groups between 1 and 14 years of age. The burden of asthma gradually decreased from 1990 to 2010. However, during the last decade (2010-2019), prevalence increased by 8.2%, as did incidence by 11.3%, whereas mortality and DALYs decreased by 23.3 and 1.6%, respectively. Finally, the burden of asthma displayed a heterogeneous pattern of disease at the subnational level. In conclusion, asthma causes a significant health loss in Mexico that differentially affects the population distributed among the states of the country, thus causing health disparities that should be addressed to provide sustainable asthma diagnosis and control to reduce its burden, especially at early stages of life.

Keywords

Allergic diseases; Atopic march; Burden of disease; Chronic respiratory diseases; DALYs; Epidemiology; Incidence; Prevalence

Subject

Public Health and Healthcare, Public Health and Health Services

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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