Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Medication Review With Follow-up for End-stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated With Medication. A Systematic Review

Version 1 : Received: 16 June 2023 / Approved: 16 June 2023 / Online: 16 June 2023 (10:13:13 CEST)

A peer-reviewed article of this Preprint also exists.

Pereira-Céspedes, A.; Jiménez-Morales, A.; Palomares-Bayo, M.; Martínez-Martínez, F.; Calleja-Hernández, M.Á. Medication Review with Follow-Up for End-Stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated with Medication—A Systematic Review. J. Clin. Med. 2023, 12, 5080. Pereira-Céspedes, A.; Jiménez-Morales, A.; Palomares-Bayo, M.; Martínez-Martínez, F.; Calleja-Hernández, M.Á. Medication Review with Follow-Up for End-Stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated with Medication—A Systematic Review. J. Clin. Med. 2023, 12, 5080.

Abstract

(1) Background: This article reviews the available scientific literature on drug-related problems and negative outcomes associated with medications identified by medication review with follow-up for end-stage renal disease and discussed with the physicians; (2) Methods: A systematic review was conducted of the scientific literature retrieved from the following databases: MEDLINE (via PubMed), Web of Science, SCOPUS, Cochrane Library: The Cochrane Central Register and Control Trials (CENTRAL) and Literatura Latinoamericana y del Caribe (LILACS), Medicina en Español (MEDES), and the SciELO bibliographic database (collection of scientific journals). The following terms were used as descriptors and searched in free text: "end-stage renal disease", "medication review", and "drug-related problems” and “negative outcomes associated with medication". The following limits were applied: "humans" and "adults (more than 18 years)”; (3) Results: A total of 59 references were recovered and after applying inclusion/exclusion criteria, 16 articles were selected. Of these selected articles, 15 provided information on drug-related problems and only 1 on negative outcomes associated with medications; (4) Conclusions: It can be concluded that drug-related problems and negative outcomes associated with medication affect patients with end-stage renal disease, mainly those receiving renal replacement therapy. More evidence is needed, especially on negative outcomes associated with medication.

Keywords

End-stage renal disease; medication review; drug-related problems; negative outcomes associated with medication.

Subject

Medicine and Pharmacology, Urology and Nephrology

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